(Q28211143)

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DNA mismatch repair and mutation avoidance pathways

scientific article (publication date: April 2002)

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Europe PubMed Central

DNA mismatch repair and mutation avoidance pathways (English)

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DNA mismatch repair

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Christophe Kunz

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Christophe Kunz

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Oliver Fleck

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Thomas M Marti

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April 2002

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Journal of Cellular Physiology

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191

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1

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28-41

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hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Kinetic measurement of the step size of DNA unwinding by Escherichia coli UvrD helicase

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

MutS mediates heteroduplex loop formation by a translocation mechanism

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Role of MED1 (MBD4) Gene in DNA repair and human cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mutator phenotypes in human colorectal carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

DNA mismatch repair catalyzed by extracts of mitotic, postmitotic, and senescent Drosophila tissues and involvement of mei-9 gene function for full activity

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch repair, gene conversion, and crossing-over in two recombination-defective mutants of Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Repair of heteroduplex DNA molecules with multibase loops in Escherichia coli

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Efficient repair of large DNA loops in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Evidence for short-patch mismatch repair in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Evolutionary origin, diversification and specialization of eukaryotic MutS homolog mismatch repair proteins

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Human DNA mismatch repair in vitro operates independently of methylation status at CpG sites

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch recognition and DNA-dependent stimulation of the ATPase activity of hMutSalpha is abolished by a single mutation in the hMSH6 subunit

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch repair, molecular switches, and signal transduction

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The swi4+ gene of Schizosaccharomyces pombe encodes a homologue of mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The high mobility group domain protein Cmb1 of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guanines

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Enhancement of MSH2–MSH3-mediated mismatch recognition by the yeast MLH1–PMS1 complex

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

DNA mismatch repair and genetic instability

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mouse models for colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Sliding clamps: a (tail)ored fit.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Binding and repair of mismatched DNA mediated by Rhp14, the fission yeast homologue of human XPA.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosis

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch repair defects in cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The human PMS2L proteins do not interact with hMLH1, a major DNA mismatch repair protein

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Base excision repair of DNA in mammalian cells

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Role of the DNA repair nucleases Rad13, Rad2 and Uve1 of Schizosaccharomyces pombe in mismatch correction.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Repair of large insertion/deletion heterologies in human nuclear extracts is directed by a 5' single-strand break and is independent of the mismatch repair system

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mutator phenotype induced by aberrant replication

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

DNA polymerase delta is required for human mismatch repair in vitro

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Frameshift mismatch recognition by the human MutS alpha complex

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Photocross-linking of the NH2-terminal Region of Taq MutS Protein to the Major Groove of a Heteroduplex DNA

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch repair deficiency associated with overexpression of the MSH3 gene

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Escherichia coli MutL loads DNA helicase II onto DNA.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mechanisms and biological effects of mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Identification of proteins of Escherichia coli and Saccharomyces cerevisiae that specifically bind to C/C mismatches in DNA.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Functional Domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA Mismatch Repair Proteins and Their Relevance to Human Hereditary Nonpolyposis Colorectal Cancer-Associated Mutations

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Nucleotide excision repair: from E. coli to man.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Cleavage of substrates with mismatched nucleotides by Flap endonuclease-1. Implications for mammalian Okazaki fragment processing.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The interaction of DNA mismatch repair proteins with human exonuclease I

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Exonuclease X of Escherichia coli. A novel 3'-5' DNase and Dnaq superfamily member involved in DNA repair.

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

A role for MLH3 in hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1

1 reference

https://api.crossref.org/works/10.1002%2FJCP.10077

21 January 2018

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10.1002/JCP.10077

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