(Q28292736)

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High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients

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High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients (English)

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author name string

J L Weeks

1

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R Zoraghi

2

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A Beasley

3

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K R Sekhar

4

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S H Francis

5

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J D Corbin

6

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language of work or name

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publication date

2005

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International Journal of Impotence Research

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17

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1

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5-9

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Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Phosphodiesterases as therapeutic targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Cloning and characterization of two splice variants of human phosphodiesterase 11A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Genomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A): comparison of rat and human PDE11A splicing variants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Re: tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

[3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Screening and Characterization of Enzyme Inhibitors as Drug Candidates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Single step isolation of sildenafil from commercially available Viagra™ tablets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

21 January 2018

Cyclic nucleotide phosphodiesterases: gene complexity, regulation by phosphorylation, and physiological implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901283

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.IJIR.3901283

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