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The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes
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1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
title
The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
main subject
leukemia
1 reference
based on heuristic
inferred from title
T-cell leukemia
1 reference
based on heuristic
inferred from title
author name string
T M Ross
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
S M Pettiford
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
P L Green
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
language of work or name
English
0 references
publication date
1 August 1996
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
number of pages
9
1 reference
based on heuristic
inferred from page(s)
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
volume
70
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
page(s)
5194-5202
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
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Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB
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The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.
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A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.
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29 September 2017
HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization
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29 September 2017
Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.
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29 September 2017
Human T-cell leukemia virus type I-induced proliferation of human immature CD2+CD3- thymocytes.
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29 September 2017
Human T-cell leukemia virus type II nucleotide sequences between env and the last exon of tax/rex are not required for viral replication or cellular transformation.
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PubMed Central
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29 September 2017
Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B
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29 September 2017
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.
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29 September 2017
Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB.
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29 September 2017
The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway
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PubMed Central
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29 September 2017
Human T-cell leukemia virus type II transforms normal human lymphocytes
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29 September 2017
Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence
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29 September 2017
Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth
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29 September 2017
Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.
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PubMed Central
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29 September 2017
Multiple sequence elements are required for regulation of human T-cell leukemia virus gene expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat
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29 September 2017
Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.
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29 September 2017
Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer
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29 September 2017
Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor
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29 September 2017
c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I
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PubMed Central
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29 September 2017
Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type 1 or the human T-cell leukemia virus type I tat proteins occurs in the absence of de novo protein synthesis
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PubMed Central
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29 September 2017
HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene
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PubMed Central
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29 September 2017
Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins
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PubMed Central
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29 September 2017
trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene
1 reference
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29 September 2017
Peripheral T-lymphocyte activation by human T-cell leukemia virus type I interferes with the CD2 but not with the CD3/TCR pathway
1 reference
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PubMed Central
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29 September 2017
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
Multiple steps are required for the induction of tumors by Abelson murine leukemia virus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
The internal methionine codons of human T-cell leukemia virus type II rex gene are not required for p24rex production or virus replication and transformation
1 reference
stated in
PubMed Central
reference URL
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29 September 2017
Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
Temporal regulation of viral and cellular gene expression during human T-lymphotropic virus type I-mediated lymphocyte immortalization
1 reference
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PubMed Central
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29 September 2017
Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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29 September 2017
Induction of the HTLV-I LTR by Jun occurs through the Tax-responsive 21-bp elements
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-1 Tax protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
In vivo cellular tropism of human T cell leukemia virus type II (HTLV-II).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
29 September 2017
A transgenic model of transactivation by the Tax protein of HTLV-I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
In vivo cellular tropism of human T-lymphotropic virus type II is not restricted to CD8+ cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
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2 June 2018
Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Direct evidence that p40x of human T-cell leukemia virus type I is a trans-acting transcriptional activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Functional relation between HTLV-II x and adenovirus E1A proteins in transcriptional activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Activation of the GM-CSF promoter by HTLV-I and -II tax proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
HTLV-1 Tax induces expression of various immediate early serum responsive genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Transactivation of Krox-20 and Krox-24 promoters by the HTLV-1 Tax protein through common regulatory elements.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Tax responsiveness of the GM-CSF promoter is mediated by mitogen-inducible sequences other than kappa B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
Transformation of CD8+ T-cells producing a strong cytopathic effect on CD4+ T-cells through syncytium formation by HTLV-II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
2 June 2018
The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
20 June 2018
HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
20 June 2018
HTLV-II transactivation is regulated by the overlapping tax/rex nonstructural genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
20 June 2018
Molecular characterization of genome of a novel human T-cell leukaemia virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
27 November 2018
Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190475
retrieved
27 November 2018
The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8764028
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMC publication ID
190475
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
PubMed publication ID
8764028
1 reference
stated in
Europe PubMed Central
PMC publication ID
190475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764028%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 October 2019
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