(Q28283135)

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Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms

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Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms (English)

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author name string

Jui Pandhare

1

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Sandra K Cooper

2

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James M Phang

3

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language of work or name

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publication date

27 January 2006

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Journal of Biological Chemistry

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281

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4

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2044-52

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A model for p53-induced apoptosis

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Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines

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The PPARs: from orphan receptors to drug discovery

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Roles of PPARs in health and disease.

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Peroxisome proliferator-activated receptors: nuclear control of metabolism

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Peroxisome-proliferator-activated receptors and cancers: complex stories

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Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells

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PPAR gamma ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells

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Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

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Peroxisome proliferator-activated receptor-gamma activation inhibits tumor progression in non-small-cell lung cancer.

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Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists

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Peroxisome proliferator-activated receptor-gamma ligands as cell-cycle modulators

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Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma.

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Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress

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15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.

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Mitochondrial reactive oxygen species in cell death signaling

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PPARs and the complex journey to obesity

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Beginnings of a signal-transduction pathway for bioenergetic control of cell survival

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Thiazolidinediones inhibit growth of gastrointestinal, biliary, and pancreatic adenocarcinoma cells through activation of the peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha pathway

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Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

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Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells

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Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines

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Troglitazone induces apoptosis via the p53 and Gadd45 pathway in vascular smooth muscle cells

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Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms

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MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.

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Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas

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PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

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Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells.

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Induction of differentiation and peroxisome proliferator-activated receptor gamma expression in colon cancer cell lines by troglitazone.

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Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells

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Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes.

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Troglitazone acts on cellular pH and DNA synthesis through a peroxisome proliferator-activated receptor gamma-independent mechanism in breast cancer-derived cell lines

1 reference

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Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species

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Organelle-specific initiation of cell death pathways

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Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

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Identifiers

10.1074/JBC.M507867200

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release_ucnqqqq52rgq3an4nbbolfgrqe

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https://api.fatcat.wiki/v0/release/ucnqqqq52rgq3an4nbbolfgrqe

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