(Q28277997)

English

p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

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p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site (English)

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author name string

A M Silverstein

1

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N Grammatikakis

2

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B H Cochran

3

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M Chinkers

4

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W B Pratt

5

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language of work or name

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publication date

7 August 1998

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Journal of Biological Chemistry

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273

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32

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20090-5

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The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase

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Cdc37: a protein kinase chaperone?

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A Novel Glycosaminoglycan-binding Protein Is the Vertebrate Homologue of the Cell Cycle Control Protein, Cdc37

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Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

1 reference

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A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37.

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CDC37 is required for p60v-src activity in yeast

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Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

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Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1 reference

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Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes

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21 January 2018

Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor

1 reference

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A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

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The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain

1 reference

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Cyclophilin-40: evidence for a dimeric complex with hsp90.

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Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor

1 reference

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Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin

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The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

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Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.

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Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70

1 reference

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21 January 2018

The mammalian heat shock protein binding immunophilin (p59/HBI) is an ATP and GTP binding protein.

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21 January 2018

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

1 reference

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Heterotetrameric structure of the human progesterone receptor

1 reference

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Subunit structure of the nonactivated human estrogen receptor

1 reference

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Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84)

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21 January 2018

The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo

1 reference

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Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

1 reference

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21 January 2018

The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.32.20090

21 January 2018

Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

1 reference

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Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus

1 reference

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21 January 2018

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10.1074/JBC.273.32.20090

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