(Q28119013)

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein (English)

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

FMRP translational regulator 1

18 January 2020

main subject

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Michael Fähling

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Andreas Steege

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Edgar Benko

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Benjamin Förstera

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Holger Scholz

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Karin M Kirschner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Pontus B Persson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Bernd J Thiele

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

19 December 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19097999%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

18 January 2020

published in

2 references

4 January 2017

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18 January 2020

volume

284

2 references

4 January 2017

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18 January 2020

2 references

4 January 2017

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18 January 2020

page(s)

4255-4266

1 reference

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The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The pathophysiology of fragile x syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Alternative splicing in the fragile X gene FMR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

New insights into fragile X syndrome: from molecules to neurobehaviors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

RNA and microRNAs in fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Whole genome microarray analysis of gene expression in subjects with fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Altered synaptic plasticity in a mouse model of fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The mGluR theory of fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Phosphorylation influences the translation state of FMRP-associated polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The fragile X syndrome: from molecular genetics to neurobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

FMRP RNA targets: identification and validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Reduced mRNA for G3BP in fragile X cells: evidence of FMR1 gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

RNAs that interact with the fragile X syndrome RNA binding protein FMRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

mRNPs, polysomes or granules: FMRP in neuronal protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Neuroanatomical, molecular genetic, and behavioral correlates of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Proneural genes and the specification of neural cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, alpha (I) mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Translational control of collagen prolyl 4-hydroxylase-alpha(I) gene expression under hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Initiation of translation in prokaryotes and eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The power of the 3' UTR: translational control and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Regulating fragile X gene transcription in the brain and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Fine structure of the human FMR1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Fragile X syndrome without CCG amplification has an FMR1 deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Two new cases of FMR1 deletion associated with mental impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

A deletion of 1.6 kb proximal to the CGG repeat of the FMR1 gene causes the clinical phenotype of the fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Ascl1 (Mash1) lineage cells contribute to discrete cell populations in CNS architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Ascl1 is required for oligodendrocyte development in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

An achaete-scute homologue essential for neuroendocrine differentiation in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Mash1 is required for neuroendocrine cell development in the glandular stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Contrasting and brain region-specific roles of neurogenin2 and mash1 in GABAergic neuron differentiation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Correct coordination of neuronal differentiation events in ventral forebrain requires the bHLH factor MASH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Roles of bHLH genes in neural stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Directed differentiation of hippocampal stem/progenitor cells in the adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

The fragile X mental retardation protein has nucleic acid chaperone properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200

Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807354200