(Q28190856)

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D B Winter

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C Kasmer

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K H Kraemer

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A R Lehmann

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P J Gearhart

Intraclonal generation of antibody mutants in germinal centres

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language of work or name

English

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publication date

June 2001

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537-41

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cites work

1 reference

7 January 2021

Clusters of point mutations are found exclusively around rearranged antibody variable genes

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7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

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7 January 2021

Targeting and subsequent selection of somatic hypermutations in the human V kappa repertoire

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7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

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7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

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7 January 2021

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

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7 January 2021

Disruption of the developmentally regulated Rev3l gene causes embryonic lethality.

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7 January 2021

Fidelity of human DNA polymerase eta

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7 January 2021

Low fidelity DNA synthesis by human DNA polymerase-eta

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7 January 2021

Mechanisms of accurate translesion synthesis by human DNA polymerase eta

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7 January 2021

DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells

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7 January 2021

Two novel human and mouse DNA polymerases of the polX family

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7 January 2021

Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase

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7 January 2021

Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene

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7 January 2021

DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis

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7 January 2021

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

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7 January 2021

hRAD30 mutations in the variant form of xeroderma pigmentosum

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7 January 2021

Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation

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7 January 2021

Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts

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7 January 2021

Differential expression of DNA polymerase epsilon in resting and activated B lymphocytes is consistent with an in vivo role in replication and not repair

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7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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7 January 2021

Induction of somatic mutation in a human B cell line in vitro

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7 January 2021

Xeroderma pigmentosum

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7 January 2021

Xeroderma pigmentosum variant: response to etretinate

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7 January 2021

Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, “minor” D segments or D-D recombination 1 1Edited By J. Karn

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7 January 2021

Impact of age on hypermutation of immunoglobulin variable genes in humans

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7 January 2021

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta

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7 January 2021

Thymine-thymine dimer bypass by yeast DNA polymerase zeta

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7 January 2021

Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta

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7 January 2021

Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

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7 January 2021

Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes

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7 January 2021

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

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7 January 2021

The expanding polymerase universe

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7 January 2021

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

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7 January 2021

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

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7 January 2021

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

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7 January 2021

Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template.

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7 January 2021

Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota

1 reference

7 January 2021