(Q28182301)

N Valerio Dorrello

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Luca Busino

Luca Busino

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Maddalena Donzelli

Maddalena Donzelli

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Giulio F Draetta

Giulio F Draetta

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author name string

Massimo Chiesa

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Dvora Ganoth

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

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language of work or name

English

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publication date

6 November 2003

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published in

Nature

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volume

426

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issue

6962

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page(s)

87-91

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02082

7 January 2021

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

1 reference

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7 January 2021

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

1 reference

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7 January 2021

Rapid destruction of human Cdc25A in response to DNA damage

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7 January 2021

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

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7 January 2021

Mammalian G1- and S-phase checkpoints in response to DNA damage

1 reference

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7 January 2021

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02082

7 January 2021

Dual mode of degradation of Cdc25 A phosphatase

1 reference

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7 January 2021

The SCF ubiquitin ligase: an extended look

1 reference

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7 January 2021

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

1 reference

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7 January 2021

Identification of a family of human F-box proteins

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7 January 2021

The F-box protein family.

1 reference

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7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

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7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

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7 January 2021

ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

1 reference

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7 January 2021

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

1 reference

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7 January 2021

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

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7 January 2021

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

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7 January 2021

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

1 reference

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7 January 2021

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

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7 January 2021

Radiosensitivity in ataxia-telangiectasia: a new explanation

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7 January 2021

Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

1 reference

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7 January 2021

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

1 reference

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7 January 2021

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

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7 January 2021

Oncogenic potential of a C.elegans cdc25 gene is demonstrated by a gain-of-function allele

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7 January 2021

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

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7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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7 January 2021