(Q28083964)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

Evidence of cancer-promoting roles for AMPK and related kinases (English)

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Tiziana Monteverde

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Nathiya Muthalagu

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Jennifer Port

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

1 reference

19 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

282

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

page(s)

4658-4671

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

MYC, metabolism, cell growth, and tumorigenesis.

25 February 2020

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Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

21 January 2018

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AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress

21 January 2018

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The regulation of AMP-activated protein kinase by H(2)O(2).

21 January 2018

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AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

21 January 2018

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The double-edged sword of AMPK signaling in cancer and its therapeutic implications

21 January 2018

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The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation

21 January 2018

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Folliculin regulates ampk-dependent autophagy and metabolic stress survival

21 January 2018

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

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The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

21 January 2018

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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

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The LKB1 tumor suppressor negatively regulates mTOR signaling

21 January 2018

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

21 January 2018

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Degradation of AMPK by a cancer-specific ubiquitin ligase

21 January 2018

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

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Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells

21 January 2018

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Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

21 January 2018

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Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

21 January 2018

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Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels

21 January 2018

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Targeting the 5'-AMP-activated protein kinase and related metabolic pathways for the treatment of prostate cancer

21 January 2018

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Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?

21 January 2018

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

21 January 2018

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21 January 2018

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

21 January 2018

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Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

21 January 2018

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Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators

21 January 2018

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5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer

21 January 2018

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LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin

21 January 2018

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LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer

21 January 2018

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AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo

21 January 2018

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21 January 2018

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21 January 2018

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Canonical and noncanonical roles of Par-1/MARK kinases in cell migration.

21 January 2018

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NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling

21 January 2018

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Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity

21 January 2018

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21 January 2018

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21 January 2018

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New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion

21 January 2018

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Transcription factor/microRNA axis blocks melanoma invasion program by miR-211 targeting NUAK1.

21 January 2018

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Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis

21 January 2018

1 reference

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Risk prediction for late-stage ovarian cancer by meta-analysis of 1525 patient samples.

21 January 2018

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Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

21 January 2018

1 reference

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Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Glioblastoma multiforme: the role of DSB repair between genotype and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Regulation of SNARK activity in response to cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

The Par-1/MARK family of protein kinases: from polarity to metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin hypersensitivity and resistance to diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Loss of Par-1a/MARK3/C-TAK1 Kinase Leads to Reduced Adiposity, Resistance to Hepatic Steatosis, and Defective Gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Microtubule affinity-regulating kinase 2 is associated with DNA damage response and cisplatin resistance in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Comprehensive molecular profiling of lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Identification and functional analysis of genes which confer resistance to cisplatin in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Wnt/Myc interactions in intestinal cancer: partners in crime

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

WNT signalling pathways as therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

The emerging roles of YAP and TAZ in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Regulation of ploidy and senescence by the AMPK-related kinase NUAK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

AMPK modulates Hippo pathway activity to regulate energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

AMPK--sensing energy while talking to other signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

Distinct thresholds govern Myc's biological output in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13534

21 January 2018

Identifiers

DOI

10.1111/FEBS.13534

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26426570%20AND%20SRC:MED&resulttype=core&format=json