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Basic biology and therapeutic implications of lncRNA

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Europe PubMed Central

Basic biology and therapeutic implications of lncRNA (English)

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author name string

O. Khorkova

1

1 reference

J. Hsiao

2

1 reference

C. Wahlestedt

3

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language of work or name

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publication date

29 June 2015

1 reference

Advanced Drug Delivery Reviews

1 reference

87

1 reference

15-24

1 reference

The Landscape of long noncoding RNA classification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

20 March 2017

Non-coding RNA in neural function, disease, and aging

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

20 March 2017

Natural antisense transcripts

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20 March 2017

Nuclear lncRNAs as epigenetic regulators-beyond skepticism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

20 March 2017

Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs

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20 March 2017

Noncoding RNA in oncogenesis: a new era of identifying key players

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20 March 2017

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs

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20 March 2017

Posttranscriptional gene regulation by long noncoding RNA

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20 March 2017

The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression

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20 March 2017

An integrated encyclopedia of DNA elements in the human genome

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20 March 2017

ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs

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20 March 2017

A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA

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20 March 2017

The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA

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20 March 2017

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

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20 March 2017

Evidence for natural antisense transcript-mediated inhibition of microRNA function

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20 March 2017

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

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20 March 2017

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase

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20 March 2017

Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer

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20 March 2017

The transcriptional landscape of the mammalian genome

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20 March 2017

TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres

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20 March 2017

Regulation of the apolipoprotein gene cluster by a long noncoding RNA

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20 March 2017

Shelterin: the protein complex that shapes and safeguards human telomeres

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20 March 2017

Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq

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20 March 2017

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

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20 March 2017

Natural antisense transcript stabilizes inducible nitric oxide synthase messenger RNA in rat hepatocytes

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20 March 2017

Landscape of transcription in human cells

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7 April 2017

The Polycomb complex PRC2 and its mark in life

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7 April 2017

Antisense transcription in the mammalian transcriptome

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7 April 2017

lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements

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7 April 2017

Comparison of splice sites reveals that long noncoding RNAs are evolutionarily well conserved

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29 September 2017

Long noncoding RNAs in cardiovascular diseases

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29 September 2017

A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus

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29 September 2017

De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA

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29 September 2017

Dark matter RNA illuminates the puzzle of genome-wide association studies

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29 September 2017

Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

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29 September 2017

HuD regulates coding and noncoding RNA to induce APP→Aβ processing

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29 September 2017

The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs

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29 September 2017

lncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Noninvasive in vivo monitoring of tissue-specific global gene expression in humans

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29 September 2017

Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project.

1 reference

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29 September 2017

Non-coding RNAs as direct and indirect modulators of epigenetic regulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Species-specific alternative splicing leads to unique expression of sno-lncRNAs

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29 September 2017

Microarray profiling and co-expression network analysis of circulating lncRNAs and mRNAs associated with major depressive disorder

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29 September 2017

LncRNAs: New Players in Apoptosis Control.

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29 September 2017

An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase

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29 September 2017

The long non-coding RNA Paupar regulates the expression of both local and distal genes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Modulation of hypoxia-signaling pathways by extracellular linc-RoR.

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29 September 2017

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

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29 September 2017

Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1)

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29 September 2017

Long non-coding RNAs in neurodevelopmental disorders

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29 September 2017

Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

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29 September 2017

Oligonucleotides for upregulating gene expression

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29 September 2017

ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians.

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29 September 2017

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

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29 September 2017

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

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29 September 2017

Promiscuous RNA binding by Polycomb repressive complex 2.

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29 September 2017

Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations

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29 September 2017

HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Negative regulation of lncRNA GAS5 by miR-21.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

lincRNAs: genomics, evolution, and mechanisms

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Guided by RNAs: X-inactivation as a model for lncRNA function.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

DNA repair at telomeres: keeping the ends intact

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Targeting long non-coding RNA to therapeutically upregulate gene expression

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Staufen-mediated mRNA decay

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29 September 2017

Gene duplication as a major force in evolution

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Non-Coding RNAs: Functional Aspects and Diagnostic Utility in Oncology

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29 September 2017

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

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29 September 2017

The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus

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29 September 2017

Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration

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29 September 2017

Non-Coding RNAs at the Gnas and Snrpn-Ube3a Imprinted Gene Loci and Their Involvement in Hereditary Disorders

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29 September 2017

Transposable elements reveal a stem cell-specific class of long noncoding RNAs

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29 September 2017

HERV-E-mediated modulation of PLA2G4A transcription in urothelial carcinoma

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29 September 2017

Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts

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29 September 2017

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation.

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29 September 2017

CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA

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29 September 2017

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Regulatory roles of natural antisense transcripts

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29 September 2017

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

29 September 2017

Epigenetic mechanisms of gene regulation during mammalian spermatogenesis

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29 September 2017

Hidden layers of human small RNAs

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29 September 2017

The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene

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29 September 2017

TF2LncRNA: identifying common transcription factors for a list of lncRNA genes from ChIP-Seq data

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2 June 2018

Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.

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2 June 2018

Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5.

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2 June 2018

Sense-antisense gene pairs: sequence, transcription, and structure are not conserved between human and mouse

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2 June 2018

Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated.

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2 June 2018

Regulation of pri-miRNA Processing by a Long Noncoding RNA Transcribed from an Ultraconserved Region

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27 November 2018

GENCODE pseudogenes

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27 November 2018

Chromosomal contact permits transcription between coregulated genes

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27 November 2018

Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

27 November 2018

YY1 binds to α-synuclein 3'-flanking region SNP and stimulates antisense noncoding RNA expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

27 November 2018

The transcribed-ultraconserved regions: a novel class of long noncoding RNAs involved in cancer susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4544752

27 November 2018

The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489

1 reference

https://pubmed.ncbi.nlm.nih.gov/26024979

12 December 2020

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inferred from PubMed ID database lookup

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