(Q27667575)

0 references

Huogen Xiao

0 references

Takuya Miura

0 references

Yoshiaki Kiso

Journal of Structural Biology

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language of work or name

1 reference

July 2011

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published in

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volume

175

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issue

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page(s)

73-84

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cites work

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Recombinant Plasmepsin 1 from the Human Malaria Parasite Plasmodium falciparum : Enzymatic Characterization, Active Site Inhibitor Design, and Structural Analysis

20 March 2017

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Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank

20 March 2017

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Structural insights into the activation of P. vivax plasmepsin

20 March 2017

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Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum

20 March 2017

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Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 A in complex with the inhibitors rs367 and rs370

20 March 2017

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Crystal structure of LexA: a conformational switch for regulation of self-cleavage

20 March 2017

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Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from plasmodium falciparum

20 March 2017

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Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum

20 March 2017

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The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry

20 March 2017

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Molecular and crystal structures of monoclinic porcine pepsin refined at 1.8 A resolution

20 March 2017

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Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

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Pushing the boundaries of molecular replacement with maximum likelihood

20 March 2017

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Solvent content of protein crystals

20 March 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

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Small dipeptide-based HIV protease inhibitors containing the hydroxymethylcarbonyl isostere as an ideal transition-state mimic

20 March 2017

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Pepstatin, a new pepsin inhibitor produced by Actinomycetes

20 March 2017

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The structure and function of the aspartic proteinases

20 March 2017

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KNI-102, a novel tripeptide HIV protease inhibitor containing allophenylnorstatine as a transition-state mimic

20 March 2017

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Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

20 March 2017

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Role of Plasmodium falciparum digestive vacuole plasmepsins in the specificity and antimalarial mode of action of cysteine and aspartic protease inhibitors

24 May 2017

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Design of potent aspartic protease inhibitors to treat various diseases

29 September 2017

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Locking the two ends of tetrapeptidic HTLV-I protease inhibitors inside the enzyme

29 September 2017

1 reference

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Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties

29 September 2017

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Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures.

29 September 2017

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Truncation and non-natural amino acid substitution studies on HTLV-I protease hexapeptidic inhibitors

29 September 2017

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Stereochemical restraints revisited: how accurate are refinement targets and how much should protein structures be allowed to deviate from them?

29 September 2017

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Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor.

29 September 2017

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Plasmepsins as potential targets for new antimalarial therapy

29 September 2017

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Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor

29 September 2017

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Design of inhibitors against HIV, HTLV-I, and Plasmodium falciparum aspartic proteases

29 September 2017

1 reference

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Structure and mechanism of the pepsin-like family of aspartic peptidases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

A distinct member of the aspartic proteinase gene family from the human malaria parasite Plasmodium falciparum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Expression and characterisation of plasmepsin I from Plasmodium falciparum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Multiple functions of pro-parts of aspartic proteinase zymogens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

High level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Gene fusion expression systems in Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Expression of soluble cloned porcine pepsinogen A in Escherichia coli.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Expression and enzymatic characterization of the soluble recombinant plasmepsin I from Plasmodium falciparum.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Chipping at large, potent human T-cell leukemia virus type 1 protease inhibitors to uncover smaller, equipotent inhibitors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Recombinant expression and partial characterization of an active soluble histo-aspartic protease from Plasmodium falciparum

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

X-ray structure of plasmepsin II complexed with a potent achiral inhibitor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Search for substrate-based inhibitors fitting the S2' space of malarial aspartic protease plasmepsin II.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Identification of peptidomimetic HTLV-I protease inhibitors containing hydroxymethylcarbonyl (HMC) isostere as the transition-state mimic

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

Design and synthesis of HIV protease inhibitors containing allophenylnorstatine as a transition-state mimic.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102120

The bioavailability of oral dosage forms of a new HIV-1 protease inhibitor, KNI-272, in beagle dogs

27 November 2018

1 reference

12 December 2020

1 reference

12 December 2020

Plasmodium falciparum: differential sensitivity in vitro to E-64 (cysteine protease inhibitor) and Pepstatin A (aspartyl protease inhibitor)

1 reference

12 December 2020

Kinetic analysis of plasmepsins I and II aspartic proteases of the Plasmodium falciparum digestive vacuole

1 reference

12 December 2020

[Kynostatin (KNI)-272--a rationally designed tripeptide inhibitor of HIV protease]

1 reference

12 December 2020

Pharmacokinetic study of a tripeptide HIV-1 protease inhibitor, KNI-174, in rats after intravenous and intraduodenal administrations

1 reference

12 December 2020

10.1016/J.JSB.2011.04.009

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21521654

1 reference