(Q27650447)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

Regulator of G protein signaling 16

6 January 2020

main subject

1 reference

Regulator of G protein signaling 10

1 reference

Regulator of G protein signaling 1

1 reference

Regulator of G protein signaling 8

1 reference

positive regulation of GTPase activity

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Francis S Willard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Adam J Kimple

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Andrew P Turnbull

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Linda J Ball

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Guillaume A Schoch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Carina Gileadi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Elizabeth F Dowler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Stephanie Q Hutsell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Michael Sundström

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Declan A Doyle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

language of work or name

English

0 references

publication date

23 April 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 January 2020

published in

1 reference

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6 January 2020

volume

105

1 reference

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6 January 2020

issue

1 reference

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6 January 2020

page(s)

6457-6462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

Molecular architecture of G o and the structural basis for RGS16-mediated deactivation

6 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

RGS2/G0S8 is a selective inhibitor of Gqalpha function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

A new family of regulators of G-protein-coupled receptors?

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

A large data set comparison of protein structures determined by crystallography and NMR: statistical test for structural differences and the effect of crystal packing.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Receptor-mediated activation of heterotrimeric G-proteins: current structural insights.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

The 7 TM G-protein-coupled receptor target family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Mammalian G proteins and their cell type specific functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

G-protein signaling: back to the future

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Regulator of G protein signaling Z1 (RGSZ1) interacts with Galpha i subunits and regulates Galpha i-mediated cell signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Regulators of G-protein signalling as new central nervous system drug targets.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Regulation of T cell activation, anxiety, and male aggression by RGS2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

G protein selectivity is a determinant of RGS2 function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Dopamine D2L receptor couples to G alpha i2 and G alpha i3 but not G alpha i1, leading to the inhibition of adenylate cyclase in transfected cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359823

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0801508105

Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0801508105

Characterization and comparison of RGS2 and RGS4 as GTPase-activating proteins for m2 muscarinic receptor-stimulated G(i).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0801508105

Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0801508105

The alpha-helical domain of Galphat determines specific interaction with regulator of G protein signaling 9

21 January 2018

1 reference

12 December 2020

The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling

1 reference

12 December 2020

Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator

1 reference

12 December 2020

Covalent immobilization of histidine-tagged proteins for surface plasmon resonance

1 reference

12 December 2020

Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins

1 reference

12 December 2020

RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0801508105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

ADS bibcode

2008PNAS..105.6457S

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

18434541

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18434541%20AND%20SRC:MED&resulttype=core&format=json