(Q27649689)

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Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating

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1 January 2020

Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating (English)

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1 January 2020

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1 January 2020

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Wei Zhang

1

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1 January 2020

Yoonsang Cho

2

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1 January 2020

James R Howe

4

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1 January 2020

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1 January 2008

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1 January 2020

Journal of Neuroscience

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1 January 2020

28

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1 January 2020

4

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1 January 2020

932-943

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1 January 2020

The glutamate receptor ion channels

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12 December 2020

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Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase

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https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Heterogeneous conductance levels of native AMPA receptors

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https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Agonist-induced isomerization in a glutamate receptor ligand-binding domain. A kinetic and mutagenetic analysis.

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https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Concentration-dependent substate behavior of native AMPA receptors

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https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Mechanism of glutamate receptor desensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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The TB structural genomics consortium crystallization facility: towards automation from protein to electron density

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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How AMPA receptor desensitization depends on receptor occupancy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Structural basis for partial agonist action at ionotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Reaction mechanism determines NMDA receptor response to repetitive stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Microsecond-to-millisecond conformational dynamics demarcate the GluR2 glutamate receptor bound to agonists glutamate, quisqualate, and AMPA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Likelihood-enhanced fast translation functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Stargazin modulates AMPA receptor gating and trafficking by distinct domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Mechanism of positive allosteric modulators acting on AMPA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Influence of agonist concentration on AMPA and kainate channels in CA1 pyramidal cells in rat hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Glutamate receptors at atomic resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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The relationship between agonist potency and AMPA receptor kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Single-channel study of the spasmodic mutation alpha1A52S in recombinant rat glycine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Dynamics of the S1S2 glutamate binding domain of GluR2 measured using 19F NMR spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Structural aspects of AMPA receptor activation, desensitization and deactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

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A stepwise mechanism for acetylcholine receptor channel gating

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Quisqualate activates a rapidly inactivating high conductance ionic channel in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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A reinterpretation of mammalian sodium channel gating based on single channel recording

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Single channel properties of cloned NMDA receptors in a human cell line: comparison with results from Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Satisfying hydrogen bonding potential in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

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The tetrameric structure of a glutamate receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of a glutamate-receptor ligand-binding core in complex with kainate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18216201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3309-07.2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18216201%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18216201%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18216201%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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