(Q27649126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

Recombination activating gene 2

27 December 2019

main subject

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Santiago Ramón-Maiques

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Tatiana G Kutateladze

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Adam G W Matthews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Alex J Kuo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Sunmi Han

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Karen S Champagne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Dmitri Ivanov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Mercedes Gallardo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Dylan Carney

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Peggie Cheung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

David N Ciccone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Kay L Walter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Paul J Utz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Yang Shi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Wei Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Marjorie A Oettinger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

English

0 references

publication date

21 November 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

450

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

7172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

1106-1110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Yng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Nonhomologous end joining and V(D)J recombination require an additional factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Partial V(D)J recombination activity leads to Omenn syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Crystal structure of the nucleosome core particle at 2.8 Å resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

SHELXL: high-resolution refinement

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Solving structures of protein complexes by molecular replacement with Phaser

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

A PHD finger motif in the C terminus of RAG2 modulates recombination activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Dynamic Regulation of Histone Lysine Methylation by Demethylases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Histone H3 Lys 4 methylation: caught in a bind?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

A COMPASS in the voyage of defining the role of trithorax/MLL-containing complexes: linking leukemogensis to covalent modifications of chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

How to keep V(D)J recombination under control

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Ordered DNA release and target capture in RAG transposition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

The C-terminal portion of RAG2 protects against transposition in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

V(D)J recombination: RAG proteins, repair factors, and regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Stepwise activation of the immunoglobulin mu heavy chain gene locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Unequal signal and coding joint formation in human V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988437

Rag mutations reveal robust alternative end joining

27 November 2018

2 references

PubMed

https://pubmed.ncbi.nlm.nih.gov/18033247

12 December 2020

inferred from PubMed ID database lookup

Crossref

https://api.crossref.org/works/10.1038%2FNATURE06431

7 January 2021

inferred from DOI database lookup

The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18033247

12 December 2020

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE06431

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE06431

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

27 December 2019

1011599205

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

18033247

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033247%20AND%20SRC:MED&resulttype=core&format=json