(Q27551184)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P30771

AAA proteins

1 reference

based on heuristic

inferred from protein domain or family

RNA helicase UPF1, UPF2-interacting domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

1 reference

14 February 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

1 reference

14 February 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

1 reference

14 February 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

1 reference

14 February 2019

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

1 reference

14 February 2019

ATPase activity

2 references

14 February 2019

Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

ribosomal small subunit binding

1 reference

14 February 2019

Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

RNA binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

mRNA binding

1 reference

14 February 2019

Global analysis of yeast mRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

cell component

mitochondrion

1 reference

14 February 2019

Overexpression of Upf1p compensates for mitochondrial splicing deficiency independently of its role in mRNA surveillance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

1 reference

14 February 2019

polysome

1 reference

14 February 2019

The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

10 September 2018

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

Subcellular localization of the yeast proteome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

silent mating-type cassette heterochromatin assembly

biological process

1 reference

14 February 2019

Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

nuclear-transcribed mRNA catabolic process

1 reference

14 February 2019

Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay

Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

translational frameshifting

1 reference

14 February 2019

Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

regulation of translational termination

1 reference

14 February 2019

Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

27 March 2018

Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30771&geneProductId=UniProtKB:P30771

27 March 2018

intracellular mRNA localization

1 reference

14 February 2019

Targeting of aberrant mRNAs to cytoplasmic processing bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

DNA recombination

1 reference

14 February 2019

Telomerase-null survivor screening identifies novel telomere recombination regulators.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

protein ubiquitination

Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

IPI

14 February 2019

Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30771

RNA helicase UPF1, UPF2-interacting domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P30771

AAA+ ATPase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P30771

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference