(Q27549979)

English

Phosphoprotein phosphatase PP4 catalytic subunit PPH3 YDR075W

fungal protein found in Saccharomyces cerevisiae S288c

YDR075W
PPH3
phosphoprotein phosphatase PP4 catalytic subunit PPH3

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No description defined

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Statements

1 reference

25 May 2022

1 reference

19 January 2017

Metallo-dependent phosphatase-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P32345

Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase family

1 reference

based on heuristic

inferred from protein domain or family

Calcineurin-like phosphoesterase

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

protein serine/threonine phosphatase activity

determination method or standard

3 references

9 May 2019

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IMP

retrieved

9 May 2019

stated in

The Saccharomyces cerevisiae gene PPH3 encodes a protein phosphatase with properties different from PPX, PP1 and PP2A.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

retrieved

9 May 2019

stated in

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

metal ion binding

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IEA

phosphoprotein phosphatase activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IEA

protein binding

determination method or standard

IPI

5 references

retrieved

9 May 2019

stated in

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IPI

retrieved

9 May 2019

stated in

A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IPI

retrieved

9 May 2019

stated in

Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IPI

retrieved

9 May 2019

stated in

Proteome survey reveals modularity of the yeast cell machinery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IPI

retrieved

9 May 2019

stated in

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IPI

cell component

nuclear periphery

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

protein phosphatase 4 complex

determination method or standard

3 references

9 May 2019

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IMP

retrieved

9 May 2019

stated in

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

retrieved

9 May 2019

stated in

Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

condensed nuclear chromosome

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

A Mec1- and PP4-dependent checkpoint couples centromere pairing to meiotic recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

nucleus

determination method or standard

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32345&geneProductId=UniProtKB:P32345

determination method or standard

IEA

cytoplasm

determination method or standard

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32345&geneProductId=UniProtKB:P32345

determination method or standard

IEA

biological process

negative regulation of glucose mediated signaling pathway

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Psy2 targets the PP4 family phosphatase Pph3 to dephosphorylate Mth1 and repress glucose transporter gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IMP

positive regulation of double-strand break repair via nonhomologous end joining

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IMP

positive regulation of nitrogen compound metabolic process

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IMP

protein dephosphorylation

determination method or standard

3 references

9 May 2019

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IMP

retrieved

9 May 2019

stated in

The Saccharomyces cerevisiae gene PPH3 encodes a protein phosphatase with properties different from PPX, PP1 and PP2A.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

retrieved

9 May 2019

stated in

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IDA

double-strand break repair via homologous recombination

determination method or standard

IGI

1 reference

retrieved

9 May 2019

stated in

Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32345

determination method or standard

IGI

has part(s)

Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P32345

Calcineurin-like phosphoesterase domain, ApaH type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P32345

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Saccharomyces Genome Database ID

1 reference

20 March 2022

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