(Q27547434)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17214

DNA/RNA-binding domain, Est1-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Telomerase activating protein Est1 family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

1 reference

8 April 2019

single-stranded DNA binding

1 reference

8 April 2019

Est1 has the properties of a single-stranded telomere end-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

telomeric DNA binding

1 reference

27 February 2018

Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

RNA binding

1 reference

8 April 2019

A bulged stem tethers Est1p to telomerase RNA in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

ribonuclease activity

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

protein binding

6 references

8 April 2019

Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

Telomerase RNA TLC1 shuttling to the cytoplasm requires mRNA export factors and is important for telomere maintenance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

ribonucleoprotein complex binding

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

telomerase RNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

cell component

nucleolus

1 reference

8 April 2019

Intracellular trafficking of yeast telomerase components.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

telomerase holoenzyme complex

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

1 reference

8 April 2019

telomere

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

1 reference

8 April 2019

cytoplasm

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

telomerase holoenzyme complex

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

biological process

telomere maintenance

1 reference

8 April 2019

A mutant with a defect in telomere elongation leads to senescence in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

telomere maintenance via telomerase

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

27 February 2018

Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

G-quadruplex DNA formation

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

mRNA export from nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

1 reference

27 February 2018

regulation of telomere maintenance via telomerase

1 reference

7 November 2018

Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

regulation of RNA stability

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

RNA phosphodiester bond hydrolysis

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

telomere maintenance via telomerase

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

regulation of telomere maintenance via telomerase

Telomerase activating protein Est1

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17214

DNA/RNA-binding domain, Est1-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17214

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference