(Q26796399)

21 June 2017

title

Fluorescence anisotropy (polarization): from drug screening to precision medicine (English)

1 reference

21 June 2017

0 references

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Hairong Zhang

1 reference

21 June 2017

Qian Wu

series ordinal

1 reference

21 June 2017

Mikhail Y Berezin

series ordinal

1 reference

21 June 2017

language of work or name

English

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publication date

4 August 2015

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Expert Opinion on Drug Discovery

21 June 2017

published in

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21 June 2017

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21 June 2017

1 reference

21 June 2017

page(s)

1145-1161

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Ultra-high resolution imaging by fluorescence photoactivation localization microscopy

21 June 2017

cites work

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Chemistry: Chemical con artists foil drug discovery

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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High-throughput fluorescence anisotropy screen for inhibitors of the oncogenic mRNA binding protein, IMP-1.

28 September 2017

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Ten years of dengue drug discovery: progress and prospects

28 September 2017

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Small-molecule procaspase activators identified using fluorescence polarization.

28 September 2017

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Protein-binding aptamer assisted signal amplification for the detection of influenza A (H1N1) DNA sequences based on quantum dot fluorescence polarization analysis

28 September 2017

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BLOOD TRIGGERED RAPID RELEASE POROUS NANOCAPSULES.

28 September 2017

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High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

28 September 2017

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Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation.

28 September 2017

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Therapeutic RNA aptamers in clinical trials

28 September 2017

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Single-stranded DNA binding protein-assisted fluorescence polarization aptamer assay for detection of small molecules.

28 September 2017

1 reference

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A multi-functional imaging approach to high-content protein interaction screening

28 September 2017

1 reference

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Opto-acoustic imaging of drug discovery biomarkers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Fluorescence polarization assays in small molecule screening

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Defining a polymethine dye for fluorescence anisotropy applications in the near-infrared spectral range

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Identification of influenza endonuclease inhibitors using a novel fluorescence polarization assay

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.

28 September 2017

1 reference

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Identification of selective class II histone deacetylase inhibitors using a novel dual-parameter binding assay based on fluorescence anisotropy and lifetime.

28 September 2017

1 reference

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Wavelength-resolved measurements of fluorescence lifetime of indocyanine green.

28 September 2017

1 reference

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Probing Rotational Viscosity in Synaptic Vesicles

28 September 2017

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Fluorescence anisotropy and resonance energy transfer: powerful tools for measuring real time protein dynamics in a physiological environment

28 September 2017

1 reference

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Fluorescence lifetime measurements and biological imaging

28 September 2017

1 reference

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Optical small animal imaging in the drug discovery process.

28 September 2017

1 reference

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Fluorescent analogs of biomolecular building blocks: design, properties, and applications

28 September 2017

1 reference

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The use of AlphaScreen technology in HTS: current status

28 September 2017

1 reference

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Near-infrared fluorescence: application to in vivo molecular imaging

28 September 2017

1 reference

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Novel trends in high-throughput screening

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Fluorescence lifetime and polarization-resolved imaging in cell biology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Covalently dye-linked, surface-controlled, and bioconjugated organically modified silica nanoparticles as targeted probes for optical imaging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Using fluorophore-labeled oligonucleotides to measure affinities of protein-DNA interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Nanoscale imaging of molecular positions and anisotropies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Scintillation proximity assays in high-throughput screening

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Carbon nanotube-quenched fluorescent oligonucleotides: probes that fluoresce upon hybridization.

28 September 2017

1 reference

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Development of the predictor HERG fluorescence polarization assay using a membrane protein enrichment approach

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Fluorescence polarization immunoassays and related methods for simple, high-throughput screening of small molecules

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Ratiometric analysis of fluorescence lifetime for probing binding sites in albumin with near-infrared fluorescent molecular probes

28 September 2017

1 reference

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Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel

28 September 2017

1 reference

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Membrane order and molecular dynamics associated with IgE receptor cross-linking in mast cells

28 September 2017

1 reference

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Aqueous ferrofluid of magnetite nanoparticles: Fluorescence labeling and magnetophoretic control

28 September 2017

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Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling

28 September 2017

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Statistical practice in high-throughput screening data analysis

28 September 2017

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Functional assays for screening GPCR targets

28 September 2017

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Small animal imaging in drug development

28 September 2017

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DNA aptamer-based bioanalysis of IgE by fluorescence anisotropy

28 September 2017

1 reference

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cAMP detection methods in HTS: selecting the best from the rest

28 September 2017

1 reference

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The impact of drug-induced QT interval prolongation on drug discovery and development

28 September 2017

1 reference

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Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer

28 September 2017

1 reference

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Fluorescence anisotropy imaging microscopy maps calmodulin binding during cellular contraction and locomotion

28 September 2017

1 reference

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Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface

28 September 2017

1 reference

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Budded baculoviruses as a tool for a homogeneous fluorescence anisotropy-based assay of ligand binding to G protein-coupled receptors: the case of melanocortin 4 receptors

31 May 2018

1 reference

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Azadioxatriangulenium (ADOTA(+)): A long fluorescence lifetime fluorophore for large biomolecule binding assay

31 May 2018

1 reference

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Probing antibody internal dynamics with fluorescence anisotropy and molecular dynamics simulations

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Structure-selective anisotropy assay for amyloid Beta oligomers

31 May 2018

1 reference

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In vivo imaging of the actin polymerization state with two-photon fluorescence anisotropy

31 May 2018

1 reference

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A high-throughput ligand competition binding assay for the androgen receptor and other nuclear receptors.

31 May 2018

1 reference

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Depolarization of surface-enhanced fluorescence: an approach to fluorescence polarization assays

31 May 2018

1 reference

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Time-resolved fluorescence anisotropy imaging applied to live cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Steady-state polarization from cylindrically symmetric fluorophores undergoing rapid restricted motion

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Fluorescence anisotropy of molecular rotors

31 May 2018

1 reference

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Utilization of fluorescence polarization and time resolved fluorescence resonance energy transfer assay formats for SAR studies: Src kinase as a model system.

21 January 2018

1 reference

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Use of red-shifted dyes in a fluorescence polarization AKT kinase assay for detection of biological activity in natural product extracts

21 January 2018

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Fluorescence polarization standard for near infrared spectroscopy and microscopy.

21 January 2018

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Time-resolved fluorescence polarization dynamics and optical imaging of Cytate: a prostate cancer receptor-targeted contrast agent

21 January 2018

1 reference

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Mobility of green fluorescent protein in hydrogel-based drug-delivery systems studied by anisotropy and fluorescence recovery after photobleaching

21 January 2018

1 reference

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Applications of fluorescence anisotropy to the study of protein-DNA interactions

21 January 2018

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Recommendations for fluorescence instrument qualification: the new ASTM Standard Guide.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Integrating sphere setup for the traceable measurement of absolute photoluminescence quantum yields in the near infrared

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Structure-based design and synthesis of fluorescent PPARalpha/delta co-agonist and its application as a probe for fluorescent polarization assay of PPARdelta ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Use of a Long-Lifetime Re(I) Complex in Fluorescence Polarization Immunoassays of High-Molecular-Weight Analytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Evaluation of fluorescent compound interference in 4 fluorescence polarization assays: 2 kinases, 1 protease, and 1 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Fluorescence Quantum Yields of a Series of Red and Near-Infrared Dyes Emitting at 600−1000 nm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Temperature effect on the fluorescence anisotropy decay dynamics of Coumarin-153 dye in Triton-X-100 and Brij-35 micellar solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Evaluation of a high-throughput fluorescence assay method for HERG potassium channel inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Biomimetic membrane platform containing hERG potassium channel and its application to drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Simulation of fluorescence anisotropy experiments: probing protein dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Momentum grows to make 'personalized' medicine more 'precise'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Precision medicine: an approach to R&D for delivering superior medicines to patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

21 January 2018

Aptamers as therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Aptamer fluorescence anisotropy sensors for adenosine triphosphate by comprehensive screening tetramethylrhodamine labeled nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Highly sensitive detection of mercury(II) ions by fluorescence polarization enhanced by gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Graphene signal amplification for sensitive and real-time fluorescence anisotropy detection of small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Polarization sensitive, three-dimensional, single-molecule imaging of cells with a double-helix system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Fluorescence nanoscopy by polarization modulation and polarization angle narrowing.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

A high-throughput screen for aggregation-based inhibition in a large compound library

21 January 2018

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Principles of Fluorescence Spectroscopy

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Fluorescence life-time imaging and steady state polarization for examining binding of fluorophores to gold nanoparticles

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

International Conference on Harmonisation; guidance on S7B Nonclinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals; availability. Notice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4871695

Scintillation proximity assay

28 November 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

Temperature mapping near plasmonic nanostructures using fluorescence polarization anisotropy

21 January 2018

1 reference

12 December 2020

Early evaluation of compound QT prolongation effects: a predictive 384-well fluorescence polarization binding assay for measuring hERG blockade

1 reference

12 December 2020

Fluorescence polarization/anisotropy approaches to study protein-ligand interactions: effects of errors and uncertainties

1 reference

12 December 2020

Two-Photon Excitation in Fluorescence Polarization Receptor-Ligand Binding Assay

1 reference

12 December 2020

A convenient sandwich assay of thrombin in biological media using nanoparticle-enhanced fluorescence polarization

1 reference

12 December 2020

Cy3B: improving the performance of cyanine dyes

1 reference

12 December 2020

Fluorescence polarization-based assay using N-glycan-conjugated quantum dots for screening in hemagglutinin blockers for influenza A viruses

1 reference

12 December 2020

Nanoparticle metrology standards based on the time-resolved fluorescence anisotropy of silica colloids

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

7 January 2021

inferred from DOI database lookup

Azadioxatriangulenium: a long fluorescence lifetime fluorophore for large biomolecule binding assay

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1075001

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1517/17460441.2015.1075001

1 reference

21 June 2017

0 references

1 reference