(Q24794593)

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Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha

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20 August 2019

11 December 2019

19 December 2019

22 December 2019

20 September 2020

22 December 2020

Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha (English)

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acute respiratory distress syndrome

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20 August 2019

11 December 2019

19 December 2019

22 December 2019

physiological phenomenon

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20 August 2019

DNA-binding protein

1 reference

11 December 2019

nuclear protein

1 reference

19 December 2019

transcription factor

2 references

22 December 2019

22 December 2020

oxidative stress

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author name string

John J Haddad

1

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language of work or name

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publication date

February 2003

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1 February 2003

5 references

20 August 2019

11 December 2019

19 December 2019

22 December 2019

22 December 2020

5 references

20 August 2019

11 December 2019

19 December 2019

22 December 2019

22 December 2020

7

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1

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47-54

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7 April 2017

Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.

1 reference

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7 April 2017

Oxygen-regulated transcription factors and their role in pulmonary disease

1 reference

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7 April 2017

Nitric oxide: a pro-inflammatory mediator in lung disease?

1 reference

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7 April 2017

Airway pressure release ventilation increases cardiac performance in patients with acute lung injury/adult respiratory distress syndrome

1 reference

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7 April 2017

The acute effects of body position strategies and respiratory therapy in paralyzed patients with acute lung injury

1 reference

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7 April 2017

Toward a better ventilation strategy for patients with acute lung injury

1 reference

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7 April 2017

High frequency oscillatory ventilation attenuates the activation of alveolar macrophages and neutrophils in lung injury

1 reference

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7 April 2017

HIF-1 and tumor progression: pathophysiology and therapeutics

1 reference

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7 April 2017

The biphasic immunoregulation of pyrimidylpiperazine (Y-40138) is IL-10 sensitive and requires NF-kappa B targeting in the alveolar epithelium

1 reference

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7 April 2017

Oxygen-evoked Na+ transport in rat fetal distal lung epithelial cells

1 reference

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7 April 2017

HIF-1 and human disease: one highly involved factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

7 April 2017

Recombinant human interleukin (IL)-1 beta-mediated regulation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) stabilization, nuclear translocation and activation requires an antioxidant/reactive oxygen species (ROS)-sensitive mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

7 April 2017

Activation of type II alveolar epithelial cells during acute endotoxemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

7 April 2017

Oxygen-sensitive pro-inflammatory cytokines, apoptosis signaling and redox-responsive transcription factors in development and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Oxygen homeostasis, thiol equilibrium and redox regulation of signalling transcription factors in the alveolar epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

1 reference

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28 September 2017

Functional genomics of oxidant-induced lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Transcriptional mechanisms of acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Regulation of experimental lung inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Enhanced susceptibility to pulmonary infection with Burkholderia cepacia in Cftr(-/-) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

HIF-1 and mechanisms of hypoxia sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

NF-kappaB blockade reduces the O2-evoked rise in Na+ conductance in fetal alveolar cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Chemioxyexcitation (delta pO2/ROS)-dependent release of IL-1 beta, IL-6 and TNF-alpha: evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Oxygen regulation of gene expression: a study in opposites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Attenuation of lung reperfusion injury after transplantation using an inhibitor of nuclear factor-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Lung redox homeostasis: emerging concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Role of redox potential and reactive oxygen species in stress signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Control of mucin transcription by diverse injury-induced signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Effects of antibiotic therapy on Pseudomonas aeruginosa-induced lung injury in a rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

Biological markers of acute lung injury: prognostic and pathogenetic significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 September 2017

The effects of two antiinflammatory pretreatments on bacterial-induced lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

30 May 2018

Assessment of operative risk for patients with advanced lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

30 May 2018

Acute lung injury: functional genomics and genetic susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Involvement of hypoxia-inducible factor 1 in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Nuclear factor-kappa B-independent regulation of lipopolysaccharide-mediated interleukin-6 biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Redox regulation of TNF-alpha biosynthesis: augmentation by irreversible inhibition of gamma-glutamylcysteine synthetase and the involvement of an IkappaB-alpha/NF-kappaB-independent pathway in alveolar epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

L-Buthionine-(S,R)-sulfoximine, an irreversible inhibitor of gamma-glutamylcysteine synthetase, augments LPS-mediated pro-inflammatory cytokine biosynthesis: evidence for the implication of an IkappaB-alpha/NF-kappaB insensitive pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Anti-inflammatory effect of adenovirus-mediated IkappaBalpha overexpression in respiratory epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Amiloride blockades lipopolysaccharide-induced proinflammatory cytokine biosynthesis in an IkappaB-alpha/NF-kappaB-dependent mechanism. Evidence for the amplification of an antiinflammatory pathway in the alveolar epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

An immediate endothelial cell signaling response to lung ischemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

A randomized, controlled trial of advanced care planning discussions during preoperative evaluations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Nuclear factor-kappab blockade attenuates but does not abrogate lipopolysaccharide-dependent tumor necrosis factor-alpha biosynthesis in alveolar epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Genetic susceptibility to irritant-induced acute lung injury in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Hepatic cryoablation, but not radiofrequency ablation, results in lung inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154109

28 November 2018

Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue factor expression in vital organs during murine traumatic shock: role of transcription factors AP-1 and NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of γ-glutamylcysteine synthetase messenger rna expression in lungs of smokers and patients with chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human macrophages by mechanical ventilation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen-independent upregulation of vascular endothelial growth factor and vascular barrier dysfunction during ventilated pulmonary ischemia in isolated ferret lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic cryoablation-induced acute lung injury: histopathologic findings

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hypoxia increases alveolar macrophage tumor necrosis factor activity and alters NF-kappaB expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic cryoablation-induced acute lung injury: pulmonary hemodynamic and permeability effects in a sheep model

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The course and prognosis of different forms of chronic airways obstruction in a sample from the general population

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-1 activation and cyclo-oxygenase-2 induction are early reperfusion-independent inflammatory events in hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary immunobiology and inflammation in pulmonary diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ex vivo differential expression of apoptosis signaling cofactors in the developing perinatal lung: essential role of oxygenation during the transition from placental to pulmonary-based respiration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 inhibits pulmonary NF-kappaB activation and lung injury induced by hepatic ischemia-reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxidases wheezing their way into asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12617740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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