(Q24629399)

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The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

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The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1 (English)

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author name string

W A May

1

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S L Lessnick

2

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B S Braun

3

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M Klemsz

4

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B C Lewis

5

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L B Lunsford

6

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R Hromas

7

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C T Denny

8

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language of work or name

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publication date

December 1993

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Molecular and Cellular Biology

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13

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12

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7393-8

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1 reference

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7 April 2017

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

1 reference

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1 reference

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7 April 2017

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

1 reference

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Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

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7 April 2017

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

1 reference

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7 April 2017

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1 reference

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Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

1 reference

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27 September 2017

The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing's sarcoma, encodes a transcriptional activator with DNA-binding specificities distinct from other Ets family members

1 reference

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Localization of the c-ets-2 transactivation domain

1 reference

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The Ets family of transcription factors

1 reference

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A membrane-associated, carbohydrate-modified form of the v-abl protein that cannot be phosphorylated in vivo or in vitro

1 reference

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c-ets-2 protooncogene has mitogenic and oncogenic activity

1 reference

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A modified CAT expression vector with convenient cloning sites

1 reference

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Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for the leukemogenicity of E26 virus

1 reference

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27 September 2017

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

1 reference

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BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

1 reference

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27 September 2017

Oncogenic conversion by regulatory changes in transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364810

27 September 2017

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364810

27 September 2017

Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complex

1 reference

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27 September 2017

The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors

1 reference

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27 September 2017

DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism

1 reference

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27 September 2017

Characterization of the ets oncogene family member, fli-1.

1 reference

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Cytogenetic characterization of selected small round cell tumors of childhood

1 reference

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Spi-1 is a putative oncogene in virally induced murine erythroleukaemias.

1 reference

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v-myb and v-ets transform chicken erythroid cells and cooperate both in trans and in cis to induce distinct differentiation phenotypes.

1 reference

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Ets1, when fused to the GAL4 DNA binding domain, efficiently enhances galactose promotor dependent gene expression in yeast

1 reference

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C-ets-1 protooncogene expression alters the growth properties of immortalized rat fibroblasts

1 reference

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30 May 2018

A novel modulator domain of Ets transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8246959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8246959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1 reference

https://pubmed.ncbi.nlm.nih.gov/8246959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of an acidic transcriptional activator in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8246959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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