(Q24622950)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

X-ray repair cross complementing 4

7 February 2020

main subject

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jean-Pierre de Villartay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

Jean-Baptiste Charbonnier

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Pascal Drevet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Sonia Baconnais

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Jeremy Amram

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

José A Márquez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Raphaël Guerois

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Isabelle Callebaut

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

language of work or name

English

0 references

publication date

18 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

7 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

108

1 reference

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7 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

12663-12668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

7 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

The DNA-damage response in human biology and disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Synapsis of DNA ends by DNA-dependent protein kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Crystal structure of an Xrcc4-DNA ligase IV complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Structural Basis of the 9-Fold Symmetry of Centrioles

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Crystal structure of human XLF: a twist in nonhomologous DNA end-joining

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Features and development of Coot

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Molecular replacement with MOLREP

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

DNA-PK autophosphorylation facilitates Artemis endonuclease activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

XLF regulates filament architecture of the XRCC4·ligase IV complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Collaboration and competition between DNA double‐strand break repair pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

V(D)J recombination deficiencies

27 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

27 September 2017

https://api.crossref.org/works/10.1073%2FPNAS.1100758108

Refinement of protein structures into low-resolution density maps using rosetta

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

New applications of simulated annealing in X-ray crystallography and solution NMR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150875

Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1100758108

Electron microscopy of Xrcc4 and the DNA ligase IV-Xrcc4 DNA repair complex.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1100758108

21 January 2018

Identifiers

DOI

10.1073/PNAS.1100758108

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

ADS bibcode

2011PNAS..10812663R

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

21768349

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768349%20AND%20SRC:MED&resulttype=core&format=json