(Q24651163)

English

Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer

scientific article published on October 20, 2003

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

0 references

Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer (English)

0 references

0 references

colorectal cancer

1 reference

based on heuristic

inferred from title

metastatic colon cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

1 reference

10.1038/SJ.BJC.6601335

https://api.crossref.org/works/10.1038/SJ.BJC.6601335

21 March 2024

author name string

W. Ichikawa

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

H. Uetake

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

Y. Shirota

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

H. Yamada

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

T. Takahashi

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

Z. Nihei

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

K. Sugihara

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

Y. Sasaki

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

R. Hirayama

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

language of work or name

0 references

publication date

20 October 2003

0 references

full work available at URL

https://www.nature.com/articles/6601335.pdf

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

https://europepmc.org/articles/PMC2394351

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

https://europepmc.org/articles/PMC2394351?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14562021

21 March 2024

http://www.nature.com/articles/6601335.pdf

1 reference

10.1038/SJ.BJC.6601335

https://api.crossref.org/works/10.1038/SJ.BJC.6601335

21 March 2024

http://www.nature.com/articles/6601335

1 reference

10.1038/SJ.BJC.6601335

https://api.crossref.org/works/10.1038/SJ.BJC.6601335

21 March 2024

British Journal of Cancer

0 references

89

0 references

8

0 references

1486-92

0 references

Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

7 April 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

7 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

7 April 2017

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

7 April 2017

Angiogenic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

7 April 2017

Real time quantitative PCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

7 April 2017

Prediction of the response of colorectal cancer to systemic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

UFT: mechanism of drug action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Fluorouracil: biochemistry and pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Assessment of response to therapy in advanced breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Thymidylate synthetase - a target enzyme in cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 September 2017

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

30 May 2018

Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

30 May 2018

A novel method for real time quantitative RT-PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

30 May 2018

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

30 May 2018

Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

30 May 2018

Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

30 May 2018

Thymidine phosphorylase: its role in sensitivity and resistance to anticancer drugs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601335

21 January 2018

Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601335

21 January 2018

Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemosensitivity to 5-FU.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601335

21 January 2018

Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601335

21 January 2018

Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601335

21 January 2018

Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601335

21 January 2018

Thymidylate synthase expression in advanced colorectal cancer predicts for response to raltitrexed.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 November 2018

Combination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 November 2018

Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 November 2018

High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394351

28 November 2018

UFT plus leucovorin for metastatic colorectal cancer: Japanese experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of uridine phosphorylase in the anabolism of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced antitumor activity of 5-fluorouracil in combination with 2'-deoxyinosine in human colorectal cell lines and human colon tumor xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species differences in substrate specificity of pyrimidine nucleoside phosphorylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribose 1-phosphate metabolism in Ehrlich ascites tumor cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenoviral-mediated transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/14562021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochimica et Biophysica Acta

8

473

73

author name string

PV Danenberg

publication date

1977

1 reference

10.1038/SJ.BJC.6601335

https://api.crossref.org/works/10.1038/SJ.BJC.6601335

21 March 2024

Identifiers

10.1038/SJ.BJC.6601335

0 references

Dimensions Publication ID

0 references

PMC publication ID

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24651163&oldid=2175249553"