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English
Structure--function relationships in HIV-1 Nef.
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1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Structure--function relationships in HIV-1 Nef
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
HIV
1 reference
based on heuristic
inferred from title
author
Matthias Geyer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Oliver T Fackler
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
B M Peterlin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
language of work or name
English
0 references
publication date
1 July 2001
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
EMBO Reports
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
580-585
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
cites work
Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
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24 March 2017
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes
1 reference
stated in
PubMed Central
reference URL
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24 March 2017
Identification of the Nef-associated kinase as p21-activated kinase 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
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24 March 2017
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
1 reference
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PubMed Central
reference URL
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24 March 2017
Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
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24 March 2017
Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
1 reference
stated in
PubMed Central
reference URL
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24 March 2017
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
7 April 2017
The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
p21-activated kinase 1 plays a critical role in cellular activation by Nef.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
The structural era of endocytosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef use distinct but overlapping target sites for downregulation of cell surface CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Refined solution structure and backbone dynamics of HIV-1 Nef.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
30 May 2018
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
The role of myristoylation in the interactions between human immunodeficiency virus type I Nef and cellular proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
cAMP takes control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
Mutational analysis of the HIV nef protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11463741
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/EMBO-REPORTS/KVE141
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
OpenCitations bibliographic resource ID
2606889
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2606889
PMC publication ID
1083955
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2606889
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PubMed publication ID
11463741
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
ResearchGate publication ID
11877987
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