(Q24540261)

6 July 2017

title

DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms (English)

1 reference

6 July 2017

0 references

0 references

Changgong Li

Changgong

1 reference

6 July 2017

Lihong Chen

series ordinal

author given names

Lihong

author last names

Chen

1 reference

6 July 2017

Jiandong Chen

series ordinal

author given names

Jiandong

author last names

Chen

1 reference

6 July 2017

language of work or name

English

0 references

publication date

1 November 2002

1 reference

Molecular and Cellular Biology

6 July 2017

published in

1 reference

6 July 2017

1 reference

6 July 2017

1 reference

6 July 2017

page(s)

7562-7571

1 reference

Identification of a cryptic nucleolar-localization signal in MDM2

6 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

MDMX: a novel p53-binding protein with some functional properties of MDM2

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Mutual dependence of MDM2 and MDMX in their functional inactivation of p53

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

MDM2 interacts with MDMX through their RING finger domains

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Control of p53 ubiquitination and nuclear export by MDM2 and ARF.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

MdmX protects p53 from Mdm2-mediated degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

Differential Regulation of the p21/WAF-1 and mdm2 Genes after High-Dose UV Irradiation: p53-Dependent and p53-Independent Regulation of the mdm2 Gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

A modified p53 overcomes mdm2-mediated oncogenic transformation: a potential cancer therapeutic agent.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135668

mdmx is a negative regulator of p53 activity in vivo

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12370303

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MDM2 and MDMX inhibit the transcriptional activity of ectopically expressed SMAD proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12370303

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.22.21.7562-7571.2002

1 reference

release_on4enxwazrb6jgaf55sdnfgwle

6 July 2017

Fatcat ID

0 references

PMC publication ID

135668

1 reference

6 July 2017

1 reference