(Q24338647)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0034211

Leucine rich repeat kinase 2

1 reference

protein autophosphorylation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Ted M Dawson

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Darren J Moore

object named as

Darren J Moore

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author name string

Andrew B West

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Catherine Choi

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Shaida A Andrabi

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Xiaojie Li

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Dustin Dikeman

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Saskia Biskup

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Zhenshui Zhang

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Kah-Leong Lim

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Valina L Dawson

LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance

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language of work or name

English

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publication date

15 January 2007

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published in

Human Molecular Genetics

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volume

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issue

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page(s)

223-32

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cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Clinical features of LRRK2-associated Parkinson's disease in central Norway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

LRRK2 expression linked to dopamine-innervated areas

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Roc, a Ras/GTPase domain in complex proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Understanding the molecular causes of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Enhancement of amyloid beta 42 secretion by 28 different presenilin 1 mutations of familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Kinase activity of mutant LRRK2 mediates neuronal toxicity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Mixed-lineage kinase control of JNK and p38 MAPK pathways

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

LRRK2G2019S as a Cause of Parkinson's Disease in North African Arabs

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

The Parkinson disease gene LRRK2: evolutionary and structural insights

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Distribution of PINK1 and LRRK2 in rat and mouse brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Molecular pathophysiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

The safety and tolerability of a mixed lineage kinase inhibitor (CEP-1347) in PD

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Frequency of LRRK2 mutations in early- and late-onset Parkinson disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021

Astrocytes protect neurons from hydrogen peroxide toxicity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL471

7 January 2021