(Q24306648)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

GOA release 2020-03-11

DNA 5'-adenosine monophosphate hydrolase activity

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Tetsuya Takahashi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Masayoshi Tada

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Shuichi Igarashi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Akihide Koyama

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Hidetoshi Date

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Akio Yokoseki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Atsushi Shiga

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Yutaka Yoshida

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Shoji Tsuji

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Masatoyo Nishizawa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

English

0 references

publication date

22 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

published in

Nucleic Acids Research

1 reference

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31 December 2019

volume

1 reference

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31 December 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

3797-3809

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

31 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

The FHA domain of aprataxin interacts with the C-terminal region of XRCC1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Aprataxin, a novel protein that protects against genotoxic stress

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substrates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

AP endonuclease-independent DNA base excision repair in human cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Removal of 3'-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Ataxia-ocular motor apraxia: a syndrome mimicking ataxia-telangiectasia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Human DNA topoisomerase I: relaxation, roles, and damage control

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Disease-associated mutations inactivate AMP-lysine hydrolase activity of Aprataxin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

DNA single-strand breaks and neurodegeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

XRCC1 and DNA strand break repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Mammalian DNA single-strand break repair: an X-ra(y)ted affair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Recessive ataxia with ocular apraxia: review of 22 Portuguese patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

APE1 is the major 3'-phosphoglycolate activity in human cell extracts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Hereditary motor and sensory neuropathy associated with cerebellar atrophy (HMSNCA): clinical and neuropathological features of a Japanese family.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Hereditary motor and sensory neuropathy associated with cerebellar atrophy (HMSNCA): a new disease.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Roles of base excision repair enzymes Nth1p and Apn2p from Schizosaccharomyces pombe in processing alkylation and oxidative DNA damage

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Loss of function mechanism in aprataxin-related early-onset ataxia

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

Making AppDNA using T4 DNA ligase

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1920238

29 November 2018

Identifiers

DOI

10.1093/NAR/GKM158

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

17519253

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17519253%20AND%20SRC:MED&resulttype=core&format=json