(Q24305128)

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Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein

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Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein (English)

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Alzheimer's disease

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based on heuristic

inferred from title

autosomal recessive hypercholesterolemia

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hypercholesterolemia

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Low density lipoprotein receptor adaptor protein 1

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GOA release 2020-03-11

Amyloid beta precursor protein

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GOA release 2020-03-11

regulation of protein localization to plasma membrane

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GOA release 2020-03-11

object named as

Peter Lopez

3

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Luciano D'Adamio

object named as

Luciano D'Adamio

5

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author name string

Cristiana Noviello

1

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Pasquale Vito

2

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Mona Abdallah

4

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language of work or name

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publication date

22 August 2003

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Journal of Biological Chemistry

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278

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34

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31843-7

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Amyloid, the presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The presenilins in Alzheimer's disease--proteolysis holds the key.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Intramembrane proteolysis by presenilins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The Role of presenilins in gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Statins and the risk of dementia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

21 January 2018

Measurement of molecular interactions in living cells by fluorescence resonance energy transfer between variants of the green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304133200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M304133200

1 reference

https://api.fatcat.wiki/v0/release/lldb4q7uljbzxiasecjfzzfqvu

30 July 2022

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release_lldb4q7uljbzxiasecjfzzfqvu

1 reference

https://api.fatcat.wiki/v0/release/lldb4q7uljbzxiasecjfzzfqvu

30 July 2022

based on heuristic

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PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/lldb4q7uljbzxiasecjfzzfqvu

30 July 2022

based on heuristic

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