(Q24304419)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Structural basis of Rab5-Rabaptin5 interaction in endocytosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

RAB5A, member RAS oncogene family

1 January 2020

main subject

endocytosis

0 references

1 reference

Rabaptin, RAB GTPase binding effector protein 1

GOA release 2020-03-11

1 reference

protein homodimerization activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Peng Zhai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Jian Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Simon Terzyan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Guangpu Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Xuejun C Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

19 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

1 January 2020

published in

1 reference

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1 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

975-983

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378032%20AND%20SRC:MED&resulttype=core&format=json

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

1 January 2020

cites work

1 reference

The guanine nucleotide-binding switch in three dimensions

20 April 2017

1 reference

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

20 April 2017

1 reference

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

20 April 2017

1 reference

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

20 April 2017

1 reference

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

20 April 2017

1 reference

rabip4′ Is an Effector of rab5 and rab4 and Regulates Transport through Early Endosomes

20 April 2017

1 reference

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

20 April 2017

1 reference

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

20 April 2017

1 reference

Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5

20 April 2017

1 reference

Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex

20 April 2017

1 reference

Crystal structure of the human GGA1 GAT domain

20 April 2017

1 reference

High resolution crystal structures of human Rab5a and five mutants with substitutions in the catalytically important phosphate-binding loop

20 April 2017

1 reference

Co-operative regulation of endocytosis by three Rab5 isoforms

20 April 2017

1 reference

Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase

20 April 2017

1 reference

Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1

20 April 2017

1 reference

Multivalent endosome targeting by homodimeric EEA1

20 April 2017

1 reference

Crystal structures of a Rab protein in its inactive and active conformations

20 April 2017

1 reference

The structural GDP/GTP cycle of Rab11 reveals a novel interface involved in the dynamics of recycling endosomes

20 April 2017

1 reference

Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases

20 April 2017

1 reference

Structure of the human ADP-ribosylation factor 1 complexed with GDP

20 April 2017

1 reference

The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms

20 April 2017

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 April 2017

1 reference

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

20 April 2017

1 reference

Raster3D Version 2.0. A program for photorealistic molecular graphics

20 April 2017

1 reference

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

20 April 2017

1 reference

The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily

20 April 2017

1 reference

Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition

21 January 2018

1 reference

Biochemical and functional characterization of a recombinant GTPase, Rab5, and two of its mutants

21 January 2018

1 reference

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

21 January 2018

1 reference

rab5 controls early endosome fusion in vitro

21 January 2018

1 reference

Implications of the SNARE hypothesis for intracellular membrane topology and dynamics

21 January 2018

1 reference

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

21 January 2018

1 reference

Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

21 January 2018

1 reference

A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

21 January 2018

1 reference

Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion

21 January 2018

1 reference

Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes.

21 January 2018

1 reference

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

21 January 2018

1 reference

Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.

21 January 2018

1 reference

Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex

21 January 2018

1 reference

21 January 2018

1 reference

Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.

21 January 2018

1 reference

Multiple Rabaptin-5-like transcripts

21 January 2018

1 reference

Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis

21 January 2018

1 reference

Determinants of Rab5 interaction with the N terminus of early endosome antigen 1.

21 January 2018

1 reference

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

21 January 2018

1 reference

Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form.

21 January 2018

1 reference

Structural Basis for Activation of ARF GTPase

21 January 2018

1 reference

Conformationally variable Rab protein surface regions mapped by limited proteolysis and homology modelling

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Miscellaneous algorithms for density modification

21 January 2018

1 reference

Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation

21 January 2018

1 reference

ALSCRIPT: a tool to format multiple sequence alignments

21 January 2018

1 reference

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

21 January 2018

1 reference

Distinct structural elements of rab5 define its functional specificity.

21 January 2018

1 reference

Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes

31 March 2020

1 reference

Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution

31 March 2020

1 reference

Phosphate-binding loop and Rab GTPase function: mutations at Ser29 and Ala30 of Rab5 lead to loss-of-function as well as gain-of-function phenotype

31 March 2020

1 reference