(Q24300634)

intrinsic apoptotic signaling pathway in response to DNA damage

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

cell cycle proteins

1 reference

Europe PubMed Central

PubMed publication ID

12717439

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717439

28 December 2023

1 reference

28 December 2023

author name string

Craig Stevens

series ordinal

0 references

Linda Smith

series ordinal

0 references

Nicholas B. La Thangue

series ordinal

1 reference

Europe PubMed Central

PubMed publication ID

12717439

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717439

full work available at URL

28 December 2023

language of work or name

English

0 references

publication date

May 2003

0 references

http://www.nature.com/articles/ncb974.pdf

file format

Portable Document Format

1 reference

http://www.nature.com/articles/ncb974

28 December 2023

1 reference

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

28 December 2023

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401-9

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cites work

1 reference

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter.

21 January 2018

1 reference

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

21 January 2018

1 reference

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

7 January 2021

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7 January 2021

Sibling rivalry in the E2F family

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7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

7 January 2021

The E2F1-3 transcription factors are essential for cellular proliferation.

1 reference

7 January 2021

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

7 January 2021

Distinct roles for E2F proteins in cell growth control and apoptosis

1 reference

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

7 January 2021

Role for the p53 homologue p73 in E2F-1-induced apoptosis

1 reference

7 January 2021

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

1 reference

7 January 2021

Role of the p53-homologue p73 in E2F1-induced apoptosis

1 reference

7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

1 reference

7 January 2021

Apoptotic and growth-promoting activity of E2F modulated by MDM2

1 reference

7 January 2021

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

1 reference

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

7 January 2021

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

7 January 2021

Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

1 reference

7 January 2021

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

7 January 2021

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2

1 reference

7 January 2021

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

1 reference

7 January 2021

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

7 January 2021

Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.

1 reference

7 January 2021

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

7 January 2021

Oncogenic capacity of the E2F1 gene

1 reference

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

7 January 2021

Regulation of p53 in response to DNA damage

1 reference

7 January 2021

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

1 reference

7 January 2021

p53: puzzle and paradigm

1 reference

7 January 2021

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

7 January 2021

Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

1 reference

7 January 2021

Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators

1 reference

7 January 2021

Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor

1 reference

7 January 2021

Acetylation control of the retinoblastoma tumour-suppressor protein

1 reference

7 January 2021

1833

WC Lin

2001

1 reference