(Q24296752)

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Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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heart arrhythmia

0 references

FKBP prolyl isomerase 1B

1 reference

GOA release 2020-03-11

Ryanodine receptor 2

1 reference

GOA release 2020-03-11

calcium ion transport into cytosol

1 reference

GOA release 2020-03-11

FK506 binding protein 1b

1 reference

GOA release 2020-03-11

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Jianmin Xiao

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Xixi Tian

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Peter P Jones

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Jeff Bolstad

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Huihui Kong

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Ruiwu Wang

6

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Lin Zhang

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Anne M Gillis

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sidney Fleischer

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Michael Kotlikoff

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Julio A Copello

12

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

S R Wayne Chen

13

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8 January 2020

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5 October 2007

1 reference

Europe PubMed Central

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8 January 2020

Journal of Biological Chemistry

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

282

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

48

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

34828-34838

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

A Novel FK506 Binding Protein Can Mediate the Immunosuppressive Effects of FK506 and Is Associated with the Cardiac Ryanodine Receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Cardiac excitation-contraction coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Dynamic regulation of sarcoplasmic reticulum Ca(2+) content and release by luminal Ca(2+)-sensitive leak in rat ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

19 March 2017

Molecular and electrophysiological bases of catecholaminergic polymorphic ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Calcium and arrhythmogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Mechanisms of Disease: ryanodine receptor defects in heart failure and fatal arrhythmia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Regulation of ryanodine receptors by FK506 binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

FKBP12.6 overexpression decreases Ca2+ spark amplitude but enhances [Ca2+]i transient in rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Characterization of Recombinant Skeletal Muscle (Ser-2843) and Cardiac Muscle (Ser-2809) Ryanodine Receptor Phosphorylation Mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

FK506 does not affect cardiac contractility and adrenergic response in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

27 September 2017

Molecular basis of Ca(2)+ activation of the mouse cardiac Ca(2)+ release channel (ryanodine receptor).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

The effect of tetracaine on stimulated contractions, sarcoplasmic reticulum Ca2+ content and membrane current in isolated rat ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

Termination of Ca2+ release during Ca2+ sparks in rat ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

Evidence that the inhibition of Na+/K(+)-ATPase activity by FK506 involves calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

30 May 2018

Atrial fibrillation is associated with increased spontaneous calcium release from the sarcoplasmic reticulum in human atrial myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Defective cardiac ryanodine receptor regulation during atrial fibrillation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Lack of effect of cADP-ribose and NAADP on the activity of skeletal muscle and heart ryanodine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: effect of FKBP-12 on single channel activity of the skeletal muscle ryanodine receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Effects of FK506 on [Ca2+]i differ in mouse and rabbit ventricular myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707423200

21 January 2018

Gender-dependent attenuation of cardiac potassium currents in type 2 diabetic db/db mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760432

29 November 2018

Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca(2+) release in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiarrhythmic effects of JTV-519, a novel cardioprotective drug, on atrial fibrillation/flutter in a canine sterile pericarditis model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of rapamycin on ryanodine receptor/Ca(2+)-release channels from cardiac muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective binding of FKBP12.6 by the cardiac ryanodine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of FK-506 on contraction and Ca2+ transients in rat cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different interactions of cardiac and skeletal muscle ryanodine receptors with FK-506 binding protein isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the immunosupressant FK506 on excitation—contraction coupling and outward K+ currents in rat ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17921453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M707423200

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17921453%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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