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Wikidata

(Q21991188)

English

Serine/threonine kinase 11

mammalian protein found in Mus musculus

  • LKB1
  • serine/threonine-protein kinase 11
  • serine/threonine-protein kinase LKB1
  • Stk11
  • liver kinase B1 homolog
  • serine/threonine-protein kinase STK11
  • mLKB1
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein serine/threonine kinase activity
determination method or standard
IDA
ISS
IEA
IMP
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISO
retrieved
14 February 2019
stated in
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
cell component
cytoplasm
determination method or standard
IDA
IEA
IMP
ISO
9 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISO
retrieved
24 April 2018
stated in
Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
24 April 2018
stated in
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
24 April 2018
stated in
The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
24 April 2018
stated in
Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
24 April 2018
stated in
Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
24 April 2018
stated in
Characterization of an alternative splice variant of LKB1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTK7&geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
nucleus
determination method or standard
IDA
IEA
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
cytoplasm
determination method or standard
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
retrieved
14 February 2019
stated in
Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA
biological process
protein phosphorylation
determination method or standard
IDA
ISS
IEA
IMP
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
ISO
retrieved
14 February 2019
stated in
Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IEA
retrieved
14 February 2019
stated in
A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation
GOA
curator
UniProt
UniProt protein ID
Q9WTK7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTK7
determination method or standard
IDA

Identifiers

 
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