(Q21984641)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P54310

membrane protein

1 reference

inferred from GOA cell component → membrane

Lipase, GDXG, putative histidine active site, protein family

1 reference

Hormone-sensitive lipase, N-terminal domain, protein family

1 reference

Alpha/beta hydrolase fold-3, protein family

1 reference

Lipase, GDXG, putative serine active site, protein family

1 reference

rRNA primary transcript binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

lipase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

1 reference

14 February 2019

triglyceride lipase activity

1 reference

14 February 2019

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

hormone-sensitive lipase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

1 reference

14 February 2019

protein binding

1 reference

14 February 2019

Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

protein kinase binding

1 reference

14 February 2019

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

serine hydrolase activity

1 reference

14 February 2019

Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

hydrolase activity, acting on ester bonds

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

acylglycerol lipase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

1 reference

14 February 2019

lipid droplet

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

1 reference

14 February 2019

mitochondrion

1 reference

14 February 2019

Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

nucleus

1 reference

14 February 2019

Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

cytosol

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

extracellular space

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

cytoplasm

Association and insulin regulated translocation of hormone-sensitive lipase with PTRF

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

termination of RNA polymerase I transcription

biological process

1 reference

14 February 2019

Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

steroid metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

1 reference

14 February 2019

diacylglycerol catabolic process

lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

1 reference

14 February 2019

transcription initiation from RNA polymerase I promoter

1 reference

14 February 2019

Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

lipid catabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

14 February 2019

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

long-chain fatty acid catabolic process

1 reference

14 February 2019

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

metabolism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54310&geneProductId=UniProtKB:P54310

1 reference

24 April 2018

triglyceride catabolic process

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310

14 February 2019

14 February 2019

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54310