(Q21980211)

Transcription factor, T-box

1 reference

T-box superfamily

1 reference

Transcription factor, T-box, region of unknown function, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

1 reference

14 February 2019

sequence-specific DNA binding

DNA-binding transcription repressor activity, RNA polymerase II-specific

4 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70324&geneProductId=UniProtKB:P70324

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70324&geneProductId=UniProtKB:P70324

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

8 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

T-box 3 is expressed in the adult mouse hypothalamus and medulla

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Expression of Tbx2 and Tbx3 in the developing hypothalamic-pituitary axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Tbx3 is required for outflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

skeletal system development

biological process

roof of mouth development

IGI

1 reference

14 February 2019

Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

negative regulation of myoblast differentiation

IGI

male genitalia development

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

1 reference

14 February 2019

limb morphogenesis

1 reference

14 February 2019

Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

branching involved in mammary gland duct morphogenesis

1 reference

14 February 2019

Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

ventricular septum morphogenesis

1 reference

14 February 2019

Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

limbic system development

1 reference

14 February 2019

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

cardiac muscle cell differentiation

1 reference

14 February 2019

Molecular pathway for the localized formation of the sinoatrial node

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

mammary placode formation

embryonic digit morphogenesis

IGI

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Mouse TBX3 mutants suggest novel molecular mechanisms for Ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

heart morphogenesis

1 reference

14 February 2019

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

outflow tract morphogenesis

1 reference

14 February 2019

Tbx3 is required for outflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

negative regulation of apoptotic process

in utero embryonic development

1 reference

14 February 2019

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70324&geneProductId=UniProtKB:P70324

1 reference

27 March 2018

embryonic heart tube development

1 reference

14 February 2019

Mouse TBX3 mutants suggest novel molecular mechanisms for Ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

mammary gland development

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

stem cell population maintenance

1 reference

14 February 2019

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

1 reference

14 February 2019

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

mesoderm morphogenesis

sinoatrial node cell development

1 reference

14 February 2019

Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

cellular senescence

atrioventricular bundle cell differentiation

1 reference

14 February 2019

Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

blood vessel development

1 reference

14 February 2019

Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

positive regulation of cell cycle

regulation of cell population proliferation

1 reference

14 February 2019

Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

positive regulation of cell population proliferation

cardiac muscle cell fate commitment

1 reference

14 February 2019

Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

luteinizing hormone secretion

negative regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

5 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

14 February 2019

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

negative regulation of epithelial cell differentiation

1 reference

14 February 2019

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

positive regulation of stem cell proliferation

1 reference

14 February 2019

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

female genitalia development

anterior/posterior axis specification, embryo

embryonic forelimb morphogenesis

specification of animal organ position

1 reference

14 February 2019

Molecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

follicle-stimulating hormone secretion

embryonic hindlimb morphogenesis

1 reference

14 February 2019

Mouse TBX3 mutants suggest novel molecular mechanisms for Ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70324

Transcription factor, T-box, region of unknown function

has part(s)

1 reference

Transcription factor, T-box, conserved site

1 reference