(Q21494990)

1 reference

9 May 2019

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

cyclin-dependent protein serine/threonine kinase regulator activity

1 reference

24 April 2018

Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

protein binding

6 references

9 May 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Cdk1 is sufficient to drive the mammalian cell cycle

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

protein-containing complex binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

protein kinase activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

protein kinase binding

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

cyclin-dependent protein kinase holoenzyme complex

cell component

1 reference

24 April 2018

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

1 reference

24 April 2018

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

6 references

24 April 2018

ISS

24 April 2018

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

24 April 2018

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

cytoplasm

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

centrosome

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

7 references

9 May 2019

ISS

9 May 2019

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

7 November 2018

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

biological process

Wnt signaling pathway

1 reference

9 May 2019

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

1 reference

9 May 2019

DNA replication initiation

IMP

1 reference

9 May 2019

Cyclin E ablation in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

IMP

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

1 reference

9 May 2019

protein phosphorylation

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

9 May 2019

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

telomere maintenance

1 reference

9 May 2019

Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

regulation of protein kinase activity

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

chromosome organization involved in meiotic cell cycle

1 reference

9 May 2019

Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

homologous chromosome pairing at meiosis

1 reference

9 May 2019

Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

negative regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

G1/S transition of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

1 reference

14 February 2019

positive regulation of cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

regulation of cyclin-dependent protein serine/threonine kinase activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

mitotic cell cycle

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

regulation of mitotic nuclear division

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

homologous chromosome pairing at meiosis

positive regulation of cell population proliferation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

positive regulation of cell cycle

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

positive regulation of G1/S transition of mitotic cell cycle

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

mitotic cell cycle phase transition

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

Cyclin, C-terminal domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61457

Cyclin-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61457

Cyclin, N-terminal

1 reference

InterPro Release 71.0