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Wikidata

(Q21116488)

English

B cell CLL/lymphoma 10

mammalian protein found in Homo sapiens

  • CARD-containing apoptotic signaling protein
  • BCL10
  • CARD containing molecule enhancing NF-kB
  • c-E10
  • CARD-containing proapoptotic protein
  • cellular-E10
  • CIPER
  • CARD-like apoptotic protein
  • cellular homolog of vCARMEN
  • mammalian CARD-containing adapter molecule E10
  • CARD-containing molecule enhancing NF-kappa-B
  • mE10
  • CED-3/ICH-1 prodomain homologous E10-like regulator
  • caspase-recruiting domain-containing protein
  • Bcl-10
  • cCARMEN
  • hCLAP
  • B-cell lymphoma/leukemia 10
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
26 references
retrieved
9 May 2019
stated in
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activation
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
CLAN, a novel human CED-4-like gene
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Nurses replies to expectations of the nursing profession
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Protein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Charting the molecular links between driver and susceptibility genes in colorectal cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein-protein interactions in relation to subcellular localization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
retrieved
9 May 2019
stated in
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IPI
cell component
cytoplasm
determination method or standard
IDA
IEA
7 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IEA
retrieved
9 May 2019
stated in
CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IDA
retrieved
9 May 2019
stated in
Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IDA
retrieved
9 May 2019
stated in
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IDA
retrieved
9 May 2019
stated in
BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma
GOA
curator
UniProt
UniProt protein ID
O95999
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IDA
retrieved
9 May 2019
stated in
Equine herpesvirus protein E10 induces membrane recruitment and phosphorylation of its cellular homologue, bcl-10
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95999
determination method or standard
IDA
biological process

Identifiers

 
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