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Wikidata

(Q21108073)

English

RAB8A, member RAS oncogene family

mammalian protein found in Homo sapiens

  • mel transforming oncogene (derived from cell line NK14)- RAB8 homolog
  • mel transforming oncogene (RAB8 homolog)
  • oncogene c-mel
  • ras-related protein Rab-8A
  • ras-associated protein RAB8
  • RAB8A
  • mel transforming oncogene (derived from cell line NK14)
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
20 references
retrieved
8 April 2019
stated in
Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Final stages of cytokinesis and midbody ring formation are controlled by BRUCE
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Pitchfork regulates primary cilia disassembly and left-right asymmetry
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Functional dissection of Rab GTPases involved in primary cilium formation
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
GOA
curator
UniProt
UniProt protein ID
P61006
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Coordination of Rab8 and Rab11 in primary ciliogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Protein LidA from Legionella is a Rab GTPase supereffector
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
retrieved
8 April 2019
stated in
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006
determination method or standard
IPI
cell component
biological process

Identifiers

 
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