(Q21106691)

Protein kinase-like domain superfamily

1 reference

SH2 domain superfamily

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

Tyrosine-protein kinase Frk, SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

protein binding

5 references

8 April 2019

Rak functions as a tumor suppressor by regulating PTEN protein stability and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

Rak functions as a tumor suppressor by regulating PTEN protein stability and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

signaling receptor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

non-membrane spanning protein tyrosine kinase activity

Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

Ensembl genome database project

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

8 April 2019

Rak functions as a tumor suppressor by regulating PTEN protein stability and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

extrinsic component of cytoplasmic side of plasma membrane

EXP

cell component

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

plasma membrane

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

intracellular anatomical structure

1 reference

8 April 2019

Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

extracellular exosome

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42685&geneProductId=UniProtKB:P42685

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42685&geneProductId=UniProtKB:P42685

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42685&geneProductId=UniProtKB:P42685

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42685&geneProductId=UniProtKB:P42685

1 reference

26 September 2017

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

azurophil granule lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

specific granule lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

nucleus

3 references

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Multiple tumor suppressor pathways negatively regulate telomerase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

peptidyl-tyrosine autophosphorylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42685&geneProductId=UniProtKB:P42685

1 reference

26 September 2017

negative regulation of cell population proliferation

1 reference

8 April 2019

The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42685

1 reference

8 April 2019

cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42685&geneProductId=UniProtKB:P42685

1 reference

26 September 2017

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5710

language of work or name

English

tyrosine-protein kinase, active site

17 August 2016

has part(s)

1 reference

SH3 domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

SH2 domain

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Tyrosine-protein kinase Frk, SH2 domain

1 reference