(Q21103279)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14222

Membrane attack complex component/perforin/complement C9

1 reference

Transporter Classification Database ID

1.C.39.2.8

2 October 2019

hierarchical database ID heuristic

C2 domain, protein family

1 reference

Perforin-1, C2 domain, protein family

1 reference

Membrane attack complex component/perforin (MACPF) domain, protein family

1 reference

Membrane attack complex component/perforin domain, conserved site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

IPI

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

1 reference

8 April 2019

calcium ion binding

identical protein binding

ISS

integral component of membrane

IPI

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

8 April 2019

Human perforin employs different avenues to damage membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

1 reference

8 April 2019

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

1 reference

8 April 2019

endosome lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

1 reference

8 April 2019

cytoplasmic vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

cytolytic granule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

8 April 2019

An antimicrobial activity of cytolytic T cells mediated by granulysin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

cellular defense response

biological process

1 reference

8 April 2019

Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

immunological synapse formation

1 reference

8 April 2019

Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

cytolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

apoptotic process

1 reference

8 April 2019

Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

transmembrane transport

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

positive regulation of killing of cells of other organism

1 reference

8 April 2019

An antimicrobial activity of cytolytic T cells mediated by granulysin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

T cell mediated cytotoxicity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14222

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers

MeSH descriptor ID

D054353

subject named as

Perforin

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

0 references

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

Transporter Classification Database ID

1.C.39.2.8

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023