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Wikidata

(Q21100441)

English

Bromodomain containing 4

mammalian protein found in Homo sapiens

  • BRD4
  • chromosome-associated protein
  • mitotic chromosome-associated protein
  • bromodomain-containing protein 4
  • Protein HUNK1
  • BRD4 protein, human
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
16 references
retrieved
8 April 2019
stated in
Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
GOA
curator
UniProt
UniProt protein ID
O60885
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release
GOA
curator
UniProt
UniProt protein ID
O60885
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes
GOA
curator
UniProt
UniProt protein ID
O60885
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
GOA
curator
UniProt
UniProt protein ID
O60885
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance
GOA
curator
UniProt
UniProt protein ID
O60885
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.
GOA
curator
UniProt
UniProt protein ID
O60885
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
Search for cellular partners of human papillomavirus type 16 E2 protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
retrieved
8 April 2019
stated in
A Y2H-seq approach defines the human protein methyltransferase interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60885
determination method or standard
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
C441289
subject named as
BRD4 protein, human
0 references
PDB structure ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21100441&oldid=2022913718"