(Q21172396)

membrane protein

1 reference

inferred from GOA cell component → membrane

Protein kinase domain, protein family

1 reference

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

protein binding

9 references

8 April 2019

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

Positive regulation of apoptosis signal-regulating kinase 1 signaling by ZPR9 protein, a zinc finger protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

The protein interaction landscape of the human CMGC kinase group

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

Mxi2 promotes stimulus-independent ERK nuclear translocation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

MAP kinase kinase activity

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

cell component

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

membrane

1 reference

7 November 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46734&geneProductId=UniProtKB:P46734

cytoplasm

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

membrane

HDA

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

HDA

biological process

MAPK cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

1 reference

8 April 2019

signal transduction

1 reference

8 April 2019

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

positive regulation of protein kinase activity

1 reference

8 April 2019

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

inflammatory response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

cardiac muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

regulation of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46734&geneProductId=UniProtKB:P46734

1 reference

7 November 2017

signal transduction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

stress-activated protein kinase signaling cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

activation of protein kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

regulation of apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46734&geneProductId=UniProtKB:P46734

1 reference

7 November 2017

cellular response to vascular endothelial growth factor stimulus

1 reference

8 April 2019

miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

p38MAPK cascade

1 reference

8 April 2019

miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

positive regulation of blood vessel endothelial cell migration

1 reference

8 April 2019

miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46734

serine/threonine-protein kinase, active site

has part(s)

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

D08.811.913.696.620.682.700.565.300

Identifiers

MeSH descriptor ID

D048371

subject named as

MAP Kinase Kinase 3

0 references

MeSH tree code

0 references

D08.811.913.696.620.682.725.200.300

0 references

D12.776.476.563.565.300

0 references

D12.776.476.568.200.300

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

10 November 2015

http://www.uniprot.org/uniprot/O09110.txt?version=146

UMLS CUI

C0293760

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023