(Q21154957)

1 reference

8 April 2019

Structural requirements and dynamics of mitosin-kinetochore interaction in M phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

protein C-terminus binding

1 reference

8 April 2019

The C Terminus of Mitosin Is Essential for Its Nuclear Localization, Centromere/Kinetochore Targeting, and Dimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

protein binding

8 references

8 April 2019

Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

cell component

ciliary basal body

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

TAS

centrosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

spindle pole

1 reference

8 April 2019

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

nuclear envelope

1 reference

8 April 2019

Farnesylation of Cenp-F is required for G2/M progression and degradation after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

midbody

1 reference

8 April 2019

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

outer kinetochore

Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

TAS

8 April 2019

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

The C Terminus of Mitosin Is Essential for Its Nuclear Localization, Centromere/Kinetochore Targeting, and Dimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

CENP-F is a .ca 400 kDa kinetochore protein that exhibits a cell-cycle dependent localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

perinuclear region of cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

pronucleus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

axoneme

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

chromatin

1 reference

8 April 2019

Structural requirements and dynamics of mitosin-kinetochore interaction in M phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

chromosome, centromeric region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

4 references

8 April 2019

8 April 2019

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

6 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

The C Terminus of Mitosin Is Essential for Its Nuclear Localization, Centromere/Kinetochore Targeting, and Dimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

kinetochore

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

4 references

8 April 2019

8 April 2019

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

8 April 2019

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

regulation of G2/M transition of mitotic cell cycle

biological process

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

metaphase plate congression

1 reference

8 April 2019

Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

DNA biosynthetic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

kidney development

1 reference

8 April 2019

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

chromosome segregation

muscle organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

ventricular system development

1 reference

8 April 2019

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

mitotic spindle assembly checkpoint signaling

1 reference

8 April 2019

Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

regulation of cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

TAS

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

protein transport

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

1 reference

8 April 2019

cell population proliferation

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Mitosin/CENP-F as a negative regulator of activating transcription factor-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

kinetochore assembly

1 reference

8 April 2019

Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

mitotic cell cycle

1 reference

8 April 2019

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49454

physically interacts with

Viroporin 3a

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

BioGRID

has part(s)

Centromere protein Cenp-F, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49454

Centromere protein Cenp-F, leucine-rich repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49454

Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain

1 reference

InterPro Release 71.0