(Q15332289)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPW9

Leucine-rich repeat domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPW9

Toll-like receptor 6

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPW9

membrane protein

1 reference

inferred from GOA cell component → membrane

Toll/interleukin-1 receptor homology (TIR) domain, protein family

1 reference

Cysteine-rich flanking region, C-terminal domain, protein family

1 reference

Leucine-rich repeat, typical subtype, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

diacyl lipopeptide binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

protein heterodimerization activity

IPI

1 reference

9 May 2017

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

GOA

curator

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

IPI

lipopeptide binding

1 reference

9 May 2017

Discrimination of bacterial lipoproteins by Toll-like receptor 6

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

transmembrane signaling receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

signaling receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

lipopeptide binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

14 February 2019

Discrimination of bacterial lipoproteins by Toll-like receptor 6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

phagocytic vesicle membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

Toll-like receptor 2-Toll-like receptor 6 protein complex

1 reference

16 September 2017

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPW9&geneProductId=UniProtKB:Q9EPW9

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

membrane raft

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

intracellular anatomical structure

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPW9&geneProductId=UniProtKB:Q9EPW9

receptor complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

Toll-like receptor 2-Toll-like receptor 6 protein complex

positive regulation of NLRP3 inflammasome complex assembly

biological process

1 reference

14 February 2019

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

positive regulation of JUN kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

toll-like receptor 6 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

MyD88-dependent toll-like receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

1 reference

9 May 2017

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

1 reference

14 February 2019

defense response to bacterium

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

1 reference

9 May 2017

cellular response to diacyl bacterial lipopeptide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

3 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

cell activation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

toll-like receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

1 reference

9 May 2017

microglial cell activation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

inflammatory response

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of gene expression

response to bacterial lipoprotein

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

negative regulation of toll-like receptor 2 signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

TRIF-dependent toll-like receptor signaling pathway

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of macrophage activation

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of nitric oxide biosynthetic process

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

nitric oxide metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of inflammatory response

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of NF-kappaB transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

cellular response to oxidised low-density lipoprotein particle stimulus

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of cytokine production involved in inflammatory response

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of oxidative stress-induced neuron death

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

positive regulation of reactive oxygen species biosynthetic process

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

cellular response to amyloid-beta

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9