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Wikidata

(Q14902260)

English

Proliferating cell nuclear antigen

mammalian protein found in Mus musculus

  • cyclin
  • proliferating cell nuclear antigen
  • Pcna
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
6 references
retrieved
8 April 2019
stated in
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IPI
retrieved
8 April 2019
stated in
GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IPI
retrieved
8 April 2019
stated in
Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IPI
retrieved
8 April 2019
stated in
A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IPI
retrieved
8 April 2019
stated in
Interaction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IPI
retrieved
8 April 2019
stated in
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IPI
cell component
nucleus
determination method or standard
IDA
ISS
IEA
ISO
16 references
retrieved
16 July 2018
stated in
GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
ISS
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
ISO
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P17918
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IEA
retrieved
16 July 2018
stated in
Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
PCNA interacts with Prox1 and represses its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Fibroblast growth factor signaling regulates Dach1 expression during skeletal development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Loss of the nuclear receptor corepressor SLIRP compromises male fertility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
16 July 2018
stated in
Characterization of the testis in congenitally ubiquitin carboxy-terminal hydrolase-1 (Uch-L1) defective (gad) mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P17918&geneProductId=UniProtKB:P17918
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
ISO
ISS
18 references
retrieved
8 April 2019
stated in
GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P17918
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IEA
retrieved
8 April 2019
stated in
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Loss of the nuclear receptor corepressor SLIRP compromises male fertility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Fibroblast growth factor signaling regulates Dach1 expression during skeletal development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Characterization of the testis in congenitally ubiquitin carboxy-terminal hydrolase-1 (Uch-L1) defective (gad) mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
PCNA interacts with Prox1 and represses its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17918
determination method or standard
IBA
biological process

Identifiers

 
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