(Q14865947)

1 reference

1 reference

132673986

1 reference

132009678

1 reference

132018368

1 reference

132682678

extrinsic apoptotic signaling pathway in absence of ligand

1 reference

5q31.1

1 reference

15 May 2022

1 reference

9 May 2019

The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

regulation of immune response

1 reference

9 May 2019

T-bet regulates T-independent IgG2a class switching

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

9 May 2019

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of B cell activation

3 references

9 May 2019

Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

Differential requirements of CD45 for lymphocyte development and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of T cell activation

1 reference

9 May 2019

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of T-helper 17 cell differentiation

1 reference

9 May 2019

Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of transcription by RNA polymerase II

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

IGI

9 May 2019

M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

Interleukin 4 increases type 5 acid phosphatase mRNA expression in murine bone marrow macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

IL-4 induces IL-2 receptor p75 beta-chain gene expression and IL-2-dependent proliferation in mouse T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

Enhancer-mediated control of macrophage-specific arginase I expression

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

defense response to protozoan

1 reference

9 May 2019

Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous Leishmaniasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

24 April 2018

Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07750&geneProductId=UniProtKB:P07750

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of epithelial cell migration

IEA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of interleukin-13 production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

T-helper 2 cell cytokine production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

myeloid dendritic cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of T cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of transcription, DNA-templated

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

TCR-dependent translational control of GATA-3 enhances Th2 differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

9 May 2019

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

dendritic cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of complement-dependent cytotoxicity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of endothelial cell apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

T cell activation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

microglial cell activation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of defense response to virus by host

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of acute inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of chronic inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

regulation of proton transport

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of interleukin-10 production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of macrophage activation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

negative regulation of nitric oxide biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

regulation of inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of mononuclear cell migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of reactive oxygen species biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of eosinophil chemotaxis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

1 reference

9 May 2019

positive regulation of gene expression

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of macroautophagy

1 reference

9 May 2019

RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

activation of Janus kinase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of receptor-mediated endocytosis

1 reference

1 January 2018

IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07750&geneProductId=UniProtKB:P07750

positive regulation of cold-induced thermogenesis

1 reference

9 May 2019

Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of amyloid-beta clearance

1 reference

1 January 2018

IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07750&geneProductId=UniProtKB:P07750

B cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

1 reference

9 May 2019

positive regulation of cellular respiration

IEA

1 reference

9 May 2019

Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP/PS1 mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

positive regulation of ATP biosynthetic process

1 reference

9 May 2019

Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP/PS1 mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750

HomoloGene ID

491

1 reference

15 May 2022

PBB GE IL4 207538 at fs.png
732 × 530; 12 KB

0 references

PBB GE IL4 207539 s at fs.png
732 × 530; 12 KB

0 references

1 reference

491

1 reference

491

1 reference

20 April 2022

1 reference

20 April 2022

1 reference

20 April 2022

1 reference

20 April 2022

1 reference

20 April 2022

right coronary artery

1 reference

20 April 2022

1 reference

20 April 2022

1 reference

20 April 2022

1 reference

20 April 2022

1 reference

20 April 2022

http://identifiers.org/ncbigene/3565

exact match

1 reference

Identifiers.org

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

has part(s)

Interleukin-4/interleukin-13, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07750

Commons category

Interleukin-4 (IL-4)

0 references

Identifiers

J9U ID

987007536902705171

1 reference

National Library of Israel Names and Subjects Authority File

Library of Congress authority ID

sh91004837

1 reference