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Wikidata

(Q14864795)

English

Adenosine deaminase

mammalian protein found in Mus musculus

  • adenosine aminohydrolase
  • Ada
  • adenosine deaminase
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No label defined

No description defined

Statements

molecular function
adenosine deaminase activity
determination method or standard
IDA
IEA
IMP
ISO
19 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
ISO
retrieved
24 April 2018
stated in
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
24 April 2018
stated in
Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Brain purines in a genetic mouse model of Lesch-Nyhan disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Structural and functional analysis of the murine adenosine deaminase gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
adenosine deaminase activity
determination method or standard
IBA
IDA
IEA
IMP
ISO
20 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
ISO
retrieved
14 February 2019
stated in
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
14 February 2019
stated in
Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Brain purines in a genetic mouse model of Lesch-Nyhan disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Structural and functional analysis of the murine adenosine deaminase gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IBA
cell component
biological process
negative regulation of inflammatory response
determination method or standard
IGI
IMP
8 references
retrieved
14 February 2019
stated in
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IGI
retrieved
14 February 2019
stated in
Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IGI
retrieved
14 February 2019
stated in
A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IGI
deoxyadenosine catabolic process
determination method or standard
IDA
IMP
7 references
retrieved
14 February 2019
stated in
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Impaired Germinal Center Maturation in Adenosine Deaminase Deficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Function of murine adenosine deaminase in the gastrointestinal tract
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
dATP catabolic process
determination method or standard
IDA
IMP
5 references
retrieved
14 February 2019
stated in
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Impaired Germinal Center Maturation in Adenosine Deaminase Deficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
inosine biosynthetic process
determination method or standard
IDA
IEA
IMP
ISO
13 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
ISO
retrieved
24 April 2018
stated in
Function of murine adenosine deaminase in the gastrointestinal tract
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
24 April 2018
stated in
Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
adenosine catabolic process
determination method or standard
IDA
IEA
IMP
ISO
22 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
ISO
retrieved
24 April 2018
stated in
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Impaired Germinal Center Maturation in Adenosine Deaminase Deficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Function of murine adenosine deaminase in the gastrointestinal tract
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
24 April 2018
stated in
Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Structural and functional analysis of the murine adenosine deaminase gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
24 April 2018
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958
determination method or standard
IDA
adenosine catabolic process
determination method or standard
IBA
IDA
IEA
IMP
ISO
23 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
ISO
retrieved
14 February 2019
stated in
Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Impaired Germinal Center Maturation in Adenosine Deaminase Deficiency
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Function of murine adenosine deaminase in the gastrointestinal tract
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
14 February 2019
stated in
Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Structural and functional analysis of the murine adenosine deaminase gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IBA
inosine biosynthetic process
determination method or standard
IBA
IDA
IEA
IMP
ISO
14 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
ISO
retrieved
14 February 2019
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Function of murine adenosine deaminase in the gastrointestinal tract
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IEA
retrieved
14 February 2019
stated in
Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase
GOA
curator
UniProt
UniProt protein ID
P03958
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958
determination method or standard
IBA

Identifiers

 
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