(Q93928546)

English

Rat cytochromes P450 (CYP) specifically contribute to the reductive bioactivation of AQ4N, an alkylaminoanthraquinone-di-N-oxide anticancer prodrug

scientific article published in November 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10598746%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

Rat cytochromes P450 (CYP) specifically contribute to the reductive bioactivation of AQ4N, an alkylaminoanthraquinone-di-N-oxide anticancer prodrug (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10598746%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

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S M Raleigh

1

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11 May 2020

E Wanogho

2

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11 May 2020

M D Burke

3

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11 May 2020

L H Patterson

4

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11 May 2020

publication date

1 November 1999

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11 May 2020

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11 May 2020

29

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11 May 2020

11

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11 May 2020

1115-1122

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11 May 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Cytochrome P450 isoenzyme activities in cultured rat and mouse liver slices

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Enhanced expression of cytochrome P450 in stomach cancer

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Comparative pharmacodynamics of CYP2B induction by phenobarbital in the male and female F344/NCr rat

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Pyridine nucleotide cofactor requirements of indicine N-oxide reduction by hepatic microsomal cytochrome P-450

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Involvement of human cytochromes P450 (CYP) in the reductive metabolism of AQ4N, a hypoxia activated anthraquinone di-N-oxide prodrug

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Initial characterization of the major mouse cytochrome P450 enzymes involved in the reductive metabolism of the hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide (tirapazamine, SR 4233, WIN 59075)

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

DNA topoisomerase II-dependent cytotoxicity of alkylaminoanthraquinones and their N-oxides

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Reduced nicotinamide adenine dinucleotide-dependent reduction of tertiary amine N-oxide by liver microsomal cytochrome P-450

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-l,2,4-benzotriazine-l ,4-dioxide (SR 4233, WIN 59075) by mouse liver

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes

1 reference

https://api.crossref.org/works/10.1080%2F004982599237994

21 January 2018

Identifiers

10.1080/004982599237994

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10598746%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10598746%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

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