(Q92925351)

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Neuroprotective Effects of the Amylin Analog, Pramlintide, on Alzheimer's Disease Are Associated with Oxidative Stress Regulation Mechanisms

scientific article published on 01 January 2019

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2 May 2020

Neuroprotective Effects of the Amylin Analog, Pramlintide, on Alzheimer's Disease Are Associated with Oxidative Stress Regulation Mechanisms (English)

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2 May 2020

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2 May 2020

Gemma Casadesus

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2 May 2020

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Sarah Patrick

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2 May 2020

Rachel Corrigan

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2 May 2020

John Grizzanti

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2 May 2020

Megan Mey

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2 May 2020

Jeff Blair

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2 May 2020

Merce Pallas

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2 May 2020

Hyoung-Gon Lee

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2 May 2020

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1 January 2019

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2 May 2020

Journal of Alzheimer's Disease

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2 May 2020

69

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2 May 2020

1

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2 May 2020

157-168

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2 May 2020

Pramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells.

1 reference

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Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's disease

1 reference

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The Link between Type 2 Diabetes and Neurodegeneration: Roles for Amyloid-β, Amylin, and Tau Proteins

1 reference

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Amylin Treatment Reduces Neuroinflammation and Ameliorates Abnormal Patterns of Gene Expression in the Cerebral Cortex of an Alzheimer's Disease Mouse Model.

1 reference

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1 reference

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Multiple target of hAmylin on rat primary hippocampal neurons

1 reference

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Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method

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Altered plasma marker of oxidative DNA damage and total antioxidant capacity in patients with Alzheimer's disease

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Oxidative stress, protein modification and Alzheimer disease

1 reference

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Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development

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Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.

1 reference

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Pramlintide Antagonizes Beta Amyloid (Aβ)- and Human Amylin-Induced Depression of Hippocampal Long-Term Potentiation

1 reference

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11 February 2021

Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease

1 reference

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Potentiometric and spectroscopic studies on the copper(II) complexes of rat amylin fragments. The anchoring ability of specific non-coordinating side chains.

1 reference

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11 February 2021

Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer's Disease: Impacts on Cognitive Decline

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Oxidant/Antioxidant imbalance and the risk of Alzheimer's disease

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Link between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatment

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Advanced glycation end products and oxidative stress in type 2 diabetes mellitus

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Plasma Amylin and Cognition in Diabetes in the Absence and the Presence of Insulin Treatment

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Heme oxygenase-1 protects against Alzheimer's amyloid-β(1-42)-induced toxicity via carbon monoxide production

1 reference

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Amylin and its analogs: a friend or foe for the treatment of Alzheimer's disease?

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Type 3 diabetes is sporadic Alzheimer׳s disease: mini-review

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Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain

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FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress

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Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease.

1 reference

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Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition.

1 reference

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Heme oxygenase-1: a metabolic nike

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Copper(II)-human amylin complex protects pancreatic cells from amylin toxicity

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Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

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NADPH-oxidase activation and cognition in Alzheimer disease progression

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Actions of β-amyloid protein on human neurons are expressed through the amylin receptor

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Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction

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Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures

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Differential alterations in antioxidant capacity in cells from Alzheimer patients

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Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin

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Oxidative damage in Alzheimer's

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Neurotoxicity of human amylin in rat primary hippocampal cultures: similarity to Alzheimer's disease amyloid-beta neurotoxicity

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Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6584632

11 February 2021

Evidence for a relationship between oxidative stress and insulin action in non-insulin-dependent (type II) diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6584632

11 February 2021

Anti-inflammatory activity of amylin and CGRP in different experimental models of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6584632

11 February 2021

Induction of haem oxygenase as a defence against oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6584632

11 February 2021

Heme oxygenase is a heat shock protein and PEST protein in rat astroglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6584632

11 February 2021

Identifiers

10.3233/JAD-180421

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30958347%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30958347%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30958347%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

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