(Q91114669)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

title

Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

David M Holtzman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Yang Shi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

publication date

1 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

19 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

page(s)

759-772

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

19 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Untangling Genetic Risk for Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglial phagocytosis of live neurons

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Neurotoxic reactive astrocytes are induced by activated microglia

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Synaptic pruning by microglia is necessary for normal brain development

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The classical complement cascade mediates CNS synapse elimination

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglia regulate the number of neural precursor cells in the developing cerebral cortex

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglia promote the death of developing Purkinje cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ATP mediates rapid microglial response to local brain injury in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Physiology of microglia

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglia: Dynamic Mediators of Synapse Development and Plasticity.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The M1 and M2 paradigm of macrophage activation: time for reassessment

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Review: activation patterns of microglia and their identification in the human brain.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Exploring the full spectrum of macrophage activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Macrophage activation and polarization: nomenclature and experimental guidelines

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Invited review: Prion-like transmission and spreading of tau pathology

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Reactive Astrocytes: Production, Function, and Therapeutic Potential

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Astrocyte heterogeneity: an underappreciated topic in neurobiology

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Astrocyte barriers to neurotoxic inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Genomic analysis of reactive astrogliosis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglia and macrophages in brain homeostasis and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ApoE immunoreactivity and microglial cells in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

APOE ε4 increases risk for dementia in pure synucleinopathies

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E mediation of neuro-inflammation in a murine model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

APOε4 is associated with enhanced in vivo innate immune responses in human subjects

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

APOE genotype-specific differences in the innate immune response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

APOE genotype alters glial activation and loss of synaptic markers in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Intracellular Lipid Flux and Membrane Microdomains as Organizing Principles in Inflammatory Cell Signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E4 is deficient in inducing macrophage ABCA1 expression and stimulating the Sp1 signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ApoE facilitates the microglial response to amyloid plaque pathology.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ApoE4 Accelerates Early Seeding of Amyloid Pathology

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Allele ε4 of Apolipoprotein E Shows a Dose Effect on Age at Onset of Pick Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

1 reference

7 January 2021

Activation of human T cells by CD1 and self-lipids.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Modulatory effects of dietary lipids on immune system functions

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 Variants in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 variants: new keys to decipher Alzheimer disease pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2 sustains microglial expansion during aging and response to demyelination

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

TREM2, Microglia, and Neurodegenerative Diseases.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Elucidating the Role of TREM2 in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Missense variant in TREML2 protects against Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Complement receptor 1 (CR1) and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Mechanism and Regulation of NLRP3 Inflammasome Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Inflammasomes in the CNS.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

Novel Markers to Delineate Murine M1 and M2 Macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41577-018-0051-1

7 January 2021

10.1038/S41577-018-0051-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

PubMed publication ID

30140051

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30140051%20AND%20SRC:MED&resulttype=core&format=json