(Q90679951)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30573475%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

title

Genetic and epigenetic regulation of cardiomyocytes in development, regeneration and disease (English)

1 reference

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15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30573475%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Miao Cui

1 reference

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15 April 2020

Zhaoning Wang

series ordinal

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15 April 2020

Rhonda Bassel-Duby

series ordinal

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15 April 2020

publication date

20 December 2018

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15 April 2020

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15 April 2020

volume

145

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15 April 2020

issue

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MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts

15 April 2020

cites work

1 reference

12 December 2020

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1 reference

12 December 2020

Response of the adult newt ventricle to injury

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12 December 2020

Regeneration of the ventricular myocardium in amphibians

1 reference

12 December 2020

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5

1 reference

12 December 2020

Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo.

1 reference

12 December 2020

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C

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12 December 2020

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

1 reference

12 December 2020

Myosin heavy chain gene expression in human heart failure

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12 December 2020

Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1

1 reference

12 December 2020

The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis

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12 December 2020

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

12 December 2020

Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer.

1 reference

12 December 2020

The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development

1 reference

12 December 2020

Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4.

1 reference

12 December 2020

Ca(2+)-dependent gene expression mediated by MEF2 transcription factors.

1 reference

12 December 2020

Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart.

1 reference

12 December 2020

CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo

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12 December 2020

Calcineurin signaling and muscle remodeling

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12 December 2020

Pressure overload increases GATA4 binding activity via endothelin-1.

1 reference

12 December 2020

The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo.

1 reference

12 December 2020

Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes

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12 December 2020

Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation

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12 December 2020

Cardiac morphology and blood pressure in the adult zebrafish.

1 reference

12 December 2020

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

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12 December 2020

The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes

1 reference

12 December 2020

Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA

1 reference

12 December 2020

Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis

1 reference

12 December 2020

IGF-1 Overexpression rescues the failing heart

1 reference

12 December 2020

Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

1 reference

12 December 2020

The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene

1 reference

12 December 2020

Increasing myocardial contraction and blood pressure in C57BL/6 mice during early postnatal development.

1 reference

12 December 2020

Heart development: molecular insights into cardiac specification and early morphogenesis

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12 December 2020

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

1 reference

12 December 2020

Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation

1 reference

12 December 2020

Increased regulatory activity of the calcineurin/NFAT pathway in human heart failure

1 reference

12 December 2020

Cyclin A2 mediates cardiomyocyte mitosis in the postmitotic myocardium

1 reference

12 December 2020

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

1 reference

12 December 2020

GATA4 is essential for formation of the proepicardium and regulates cardiogenesis

1 reference

12 December 2020

Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice

1 reference

12 December 2020

BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart

1 reference

12 December 2020

Building the mammalian heart from two sources of myocardial cells

1 reference

12 December 2020

Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling after myocardial infarction in adult mice in vivo.

1 reference

12 December 2020

Regionalized sequence of myocardial cell growth and proliferation characterizes early chamber formation.

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12 December 2020

Gene regulatory networks in the evolution and development of the heart

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12 December 2020

Functional modulation of cardiac form through regionally confined cell shape changes

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12 December 2020

Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes

1 reference

12 December 2020

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

1 reference

12 December 2020

Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification

1 reference

12 December 2020

Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.

1 reference

12 December 2020

Evidence for cardiomyocyte renewal in humans

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12 December 2020

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

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12 December 2020

Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury

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12 December 2020

Return to the fetal gene program: a suggested metabolic link to gene expression in the heart

1 reference

12 December 2020

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

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12 December 2020

Reduced systolic pressure load decreases cell-cycle activity in the fetal sheep heart

1 reference

12 December 2020

Chromatin regulation by Brg1 underlies heart muscle development and disease

1 reference

12 December 2020

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors

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12 December 2020

Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes

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12 December 2020

Chromatin remodelling complex dosage modulates transcription factor function in heart development

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12 December 2020

Transient regenerative potential of the neonatal mouse heart

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12 December 2020

IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development

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12 December 2020

Relaxin promotes growth and maturation of mouse neonatal cardiomyocytes in vitro: clues for cardiac regeneration

1 reference

12 December 2020

Role of YAP/TAZ in mechanotransduction

1 reference

12 December 2020

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

1 reference

12 December 2020

LMNA cardiomyopathy: cell biology and genetics meet clinical medicine.

1 reference

12 December 2020

Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes

1 reference

12 December 2020

Differential role of Nkx2-5 in activation of the atrial natriuretic factor gene in the developing versus failing heart

1 reference

12 December 2020

Large-scale discovery of enhancers from human heart tissue

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12 December 2020

Polycomb repressive complex 2 regulates normal development of the mouse heart

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12 December 2020

PRC2 directly methylates GATA4 and represses its transcriptional activity

1 reference

12 December 2020

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.

1 reference

12 December 2020

Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth

1 reference

12 December 2020

Transcription factor pathways and congenital heart disease.

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12 December 2020

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

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12 December 2020

Heart repair by reprogramming non-myocytes with cardiac transcription factors

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12 December 2020

Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage

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12 December 2020

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

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12 December 2020

Cardiomyocyte proliferation contributes to heart growth in young humans

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12 December 2020

Signaling and transcriptional networks in heart development and regeneration

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12 December 2020

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

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12 December 2020

De novo mutations in histone-modifying genes in congenital heart disease.

1 reference

12 December 2020

Sequencing of mRNA identifies re-expression of fetal splice variants in cardiac hypertrophy.

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12 December 2020

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

1 reference

12 December 2020

Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration

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12 December 2020

Hippo pathway effector Yap promotes cardiac regeneration

1 reference

12 December 2020

Embryonic heart progenitors and cardiogenesis

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12 December 2020

Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy.

1 reference

12 December 2020

Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes

1 reference

12 December 2020

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

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12 December 2020

A proliferative burst during preadolescence establishes the final cardiomyocyte number.

1 reference

12 December 2020

MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures

1 reference

12 December 2020

Blood flow and Bmp signaling control endocardial chamber morphogenesis.

1 reference

12 December 2020

Cardiac cell lineages that form the heart

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12 December 2020

Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease

1 reference

12 December 2020

Early patterning and specification of cardiac progenitors in gastrulating mesoderm.

1 reference

12 December 2020

Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation

1 reference

12 December 2020

How to make a cardiomyocyte

1 reference

12 December 2020

Molecular regulation of cardiomyocyte differentiation

1 reference

12 December 2020

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness.

1 reference

12 December 2020

Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish

1 reference

12 December 2020

Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window

1 reference

12 December 2020

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.

1 reference

12 December 2020

Histone methylations in heart development, congenital and adult heart diseases

1 reference

12 December 2020

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice.

1 reference

12 December 2020

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

1 reference

12 December 2020

Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes

1 reference

12 December 2020

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling

1 reference

12 December 2020

No Evidence for Cardiomyocyte Number Expansion in Preadolescent Mice.

1 reference

12 December 2020

A specified therapeutic window for neuregulin-1 to regenerate neonatal heart muscle

1 reference

12 December 2020

Minor Loops in Major Folds: Enhancer-Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease

1 reference

12 December 2020

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies

1 reference

12 December 2020

Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction.

1 reference

12 December 2020

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

1 reference

12 December 2020

Metabolic remodeling in early development and cardiomyocyte maturation

1 reference

12 December 2020

Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

1 reference

12 December 2020

Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.

1 reference

12 December 2020

Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.

1 reference

12 December 2020

Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy

1 reference

12 December 2020

The chromatin-binding protein Smyd1 restricts adult mammalian heart growth

1 reference

12 December 2020

Genome-wide compendium and functional assessment of in vivo heart enhancers

1 reference

12 December 2020

Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming

1 reference

12 December 2020

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis.

1 reference

12 December 2020

The transcription factor GATA4 promotes myocardial regeneration in neonatal mice

1 reference

12 December 2020

Redirecting cardiac growth mechanisms for therapeutic regeneration

1 reference

12 December 2020

Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity.

1 reference

12 December 2020

Divergent Requirements for EZH1 in Heart Development Versus Regeneration.

1 reference

12 December 2020

The extracellular matrix protein agrin promotes heart regeneration in mice.

1 reference

12 December 2020

Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation.

1 reference

12 December 2020

Cardiac regeneration strategies: Staying young at heart.

1 reference

12 December 2020

Metabolic remodelling in hypertrophied and failing myocardium: a review.

1 reference

12 December 2020

Cardiomyocyte Regeneration: A Consensus Statement

1 reference

12 December 2020

Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics

1 reference

12 December 2020

Multi-Cellular Transcriptional Analysis of Mammalian Heart Regeneration

1 reference

12 December 2020

Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration

1 reference

12 December 2020

High Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure

1 reference

12 December 2020

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

1 reference

12 December 2020

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.

1 reference

12 December 2020

Hippo pathway deficiency reverses systolic heart failure after infarction.

1 reference

12 December 2020

ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression

1 reference

12 December 2020

Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte.

1 reference

12 December 2020

Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape.

1 reference

12 December 2020

Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq.

1 reference

12 December 2020

Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond.

1 reference

12 December 2020

α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart.

1 reference

12 December 2020

Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish.

1 reference

12 December 2020

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration.

1 reference

12 December 2020

The local microenvironment limits the regenerative potential of the mouse neonatal heart.

1 reference

12 December 2020

Therapeutic approaches for cardiac regeneration and repair

1 reference

12 December 2020

The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration

1 reference

12 December 2020

The deployment of cell lineages that form the mammalian heart

1 reference

12 December 2020

A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.171983

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30573475%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

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15 April 2020

PubMed publication ID

30573475

1 reference

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