(Q90476802)

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Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages

scientific article published on 25 June 2018

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30046278%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30046278%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

metabolic syndrome

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Hiroki Yamazaki

1

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14 April 2020

Tomoichiro Asano

10

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14 April 2020

author name string

Akifumi Kushiyama

2

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14 April 2020

Hideyuki Sakoda

3

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14 April 2020

Midori Fujishiro

4

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14 April 2020

Takeshi Yamamotoya

5

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14 April 2020

Yusuke Nakatsu

6

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14 April 2020

Takako Kikuchi

7

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14 April 2020

Sunao Kaneko

8

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14 April 2020

Hirotoshi Tanaka

9

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14 April 2020

publication date

25 June 2018

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14 April 2020

Mediators of Inflammation

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Europe PubMed Central

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14 April 2020

2018

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14 April 2020

3062319

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30046278%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

copyright license

Creative Commons Attribution 4.0 International

25 June 2018

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April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6036814/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6036814/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The control of the interaction of sex hormone-binding globulin with its receptor by steroid hormones

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nile red: a selective fluorescent stain for intracellular lipid droplets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of steroid hormones: interaction of 70 drugs with testosterone-binding globulin and corticosteroid-binding globulin in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estradiol causes the rapid accumulation of cAMP in human prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptors for androgen-binding proteins: internalization and intracellular signalling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex hormone-binding globulin stimulates chorionic gonadotrophin secretion from human cytotrophoblasts in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocyte differentiation and gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex hormone-binding globulin is synthesized in target cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen and SHBG serum concentrations in late post-menopause women

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of endocytosis in cellular uptake of sex steroids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reference intervals for testosterone, androstenedione and SHBG levels in healthy females and males from birth until old age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that fibulin family members contribute to the steroid-dependent extravascular sequestration of sex hormone-binding globulin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic endotoxemia initiates obesity and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex hormone binding globulin levels across the adult lifespan in women--the role of body mass index and fasting insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolation and characterization of murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte chemoattractant protein-1 (MCP-1): an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex hormone-binding globulin and risk of type 2 diabetes in women and men

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural analyses of sex hormone-binding globulin reveal novel ligands and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet--induced obesity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoplasmic accumulation of incompletely glycosylated SHBG enhances androgen action in proximal tubule epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SHBG, sex hormones, and inflammatory markers in older women

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with insulin receptor substrate-1 and enhances insulin actions and adipogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diverse roles for sex hormone-binding globulin in reproduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low Testosterone Associated With Obesity and the Metabolic Syndrome Contributes to Sexual Dysfunction and Cardiovascular Disease Risk in Men With Type 2 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-mediated inflammation in metabolic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low serum sex hormone-binding globulin: marker of inflammation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Mechanism of TNFα-Induced Down-Regulation of SHBG Expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Micro- and macroheterogeneity of N-glycosylation yields size and charge isoforms of human sex hormone binding globulin circulating in serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both total testosterone and sex hormone-binding globulin are independent risk factors for metabolic syndrome: results from Fangchenggang Area Male Health and Examination Survey in China

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

α-Mangostin Improves Glucose Uptake and Inhibits Adipocytes Differentiation in 3T3-L1 Cells via PPARγ, GLUT4, and Leptin Expressions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SHBG-C57BL/ksJ-db/db: A New Mouse Model to Study SHBG Expression and Regulation During Obesity Development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteocalcin and Sex Hormone Binding Globulin Compete on a Specific Binding Site of GPRC6A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Losartan reduces ensuing chronic kidney disease and mortality after acute kidney injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex Hormone Binding Globulin Modifies Testosterone Action and Metabolism in Prostate Cancer Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30046278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2018/3062319

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30046278%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30046278%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30046278%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

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